Plasma inducible degrader of the LDLR, soluble low-density lipoprotein receptor, and proprotein convertase subtilisin/kexin type 9 levels as potential biomarkers of familial hypercholesterolemia in children.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of clinical lipidology"
DOI: 10.1016/j.jacl.2017.10.003
Abstract: BACKGROUND Familial hypercholesterolemia (FH) in children is under-detected. Plasma biomarkers associated with low-density lipoprotein receptor (LDLR) function could help identifying FH children. OBJECTIVES We aim to assess the clinical value of inducible degrader of the… read more here.
Keywords: plasma; density lipoprotein; hypercholesterolemia children; low density ... See more keywords
School-based universal screening for hypercholesterolemia in children.
Sign Up to like & getrecommendations! Published in 2022 at "Pediatrics and neonatology"
DOI: 10.1016/j.pedneo.2021.12.013
Abstract: BACKGROUND In 2011, the American Academy of Pediatrics recommended universal lipid screening during childhood and adolescence. However, this approach was shown to be lacking in adherence. Only 6% of non-high-risk children received lipid screening by… read more here.
Keywords: hypercholesterolemia children; school based; based universal; universal screening ... See more keywords
Response by Kusters et al to Letter Regarding Article, "Effect of Rosuvastatin on Carotid Intima-Media Thickness in Children With Heterozygous Familial Hypercholesterolemia: The CHARON Study (Hypercholesterolemia in Children and Adolescents Taking Rosuvastatin Open Label)".
Sign Up to like & getrecommendations! Published in 2018 at "Circulation"
DOI: 10.1161/circulationaha.117.031676
Abstract: We appreciate the comments of Dr Koh regarding our recent publication in Circulation .1 We comment here on the issues raised. Undoubtedly, patients with heterozygous familial hypercholesterolemia (HeFH) should be treated with lipid-lowering medication from… read more here.
Keywords: hypercholesterolemia; rosuvastatin; hypercholesterolemia children; heterozygous familial ... See more keywords
Recent Advances on Familial Hypercholesterolemia in Children and Adolescents
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DOI: 10.3390/biomedicines10051043
Abstract: Familial hypercholesterolemia is a common autosomal hereditary disorder characterized by elevated concentrations of low-density lipoprotein cholesterol and the development of premature atherosclerosis and cardiovascular disease. Early diagnosis, as well as prompt and aggressive treatment, are… read more here.
Keywords: familial hypercholesterolemia; recent advances; hypercholesterolemia children; children adolescents ... See more keywords