Articles with "hypercholinergic state" as a keyword



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What’s wrong with the striatal cholinergic interneurons in Parkinson’s disease? Focus on intrinsic excitability

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Published in 2020 at "European Journal of Neuroscience"

DOI: 10.1111/ejn.14742

Abstract: Parkinson's disease (PD) is characterized by a degeneration of nigrostriatal dopaminergic neurons that results in a hypercholinergic state in the striatum. This hypercholinergic state contributes to the clinical signs of PD. However, the mechanisms that… read more here.

Keywords: hypercholinergic state; excitability; parkinson disease; wrong striatal ... See more keywords