Synchronous bilateral adrenalectomy in ACTH-dependent hypercortisolism: predictors, biomarkers and outcomes
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DOI: 10.1007/s12020-019-02091-9
Abstract: Hypercortisolism requires a prompt therapeutic management to reduce the risk of development of a potential fatal emergency. A synchronous bilateral adrenalectomy (SBA) is effective in recovering hypercortisolism. However, specific indications for an SBA are not… read more here.
Keywords: acth dependent; hypercortisolism; bilateral adrenalectomy; dependent hypercortisolism ... See more keywords
Do the diagnostic criteria for subclinical hypercortisolism exist?
Sign Up to like & getrecommendations! Published in 2018 at "Annales d'endocrinologie"
DOI: 10.1016/j.ando.2018.03.013
Abstract: "Subclinical hypercortisolism" (SH) refers to a condition associated with a mild chronic increase in cortisol secretion. By definition, patients with SH do not exhibit specific symptoms of overt Cushing's syndrome (such as purple striae, easy… read more here.
Keywords: hypercortisolism exist; criteria subclinical; hypercortisolism; cushing syndrome ... See more keywords
The difficulties of pseudo-Cushing's syndrome (or "non-neoplastic hypercortisolism").
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DOI: 10.1016/j.ando.2018.04.017
Abstract: Pseudo-Cushing's syndrome covers different pathological conditions responsible for mild-to-moderate ACTH-dependent hypercortisolism, related not to an ACTH-secreting tumor but rather to CRH and/or AVP hypothalamic secretion through activation of various neural pathways, in patients generally displaying… read more here.
Keywords: neoplastic hypercortisolism; difficulties pseudo; hypercortisolism; cushing syndrome ... See more keywords
Pneumocystis pneumonia can complicate medical treatment of hypercortisolism even in outpatients with Cushing's disease.
Sign Up to like & getrecommendations! Published in 2020 at "Annales d'endocrinologie"
DOI: 10.1016/j.ando.2020.11.002
Abstract: Several cases of Pneumocystosis pneumonia (PCP) have been reported, mainly in patients with severe ectopic ACTH syndrome (EAS). We report 2 cases of PCP that did not develop until after starting treatment with metyrapone, one of… read more here.
Keywords: cushing disease; medical treatment; treatment; hypercortisolism ... See more keywords
L'impact du syndrome de Cushing sur la fertilité et la grossesse.
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DOI: 10.1016/j.ando.2022.04.001
Abstract: Cushing's syndrome is defined by an endogenous or exogenous hypercortisolism. Increased cortisol, as well as increased androgens will have a negative impact on the pulsatile secretion of GnRH, thus leading to an increased risk of… read more here.
Keywords: hypercortisolism; syndrome cushing; syndrome; pregnancy ... See more keywords
Adrenocortical Carcinoma with Hypercortisolism.
Sign Up to like & getrecommendations! Published in 2018 at "Endocrinology and metabolism clinics of North America"
DOI: 10.1016/j.ecl.2018.02.003
Abstract: Adrenocortical carcinoma (ACC) is a rare and aggressive tumor. ACC may be associated with different syndromes of hormone excess, most frequently Cushing's syndrome with or without hypersecretion of androgens. Recent data suggest that cortisol excess… read more here.
Keywords: adrenocortical carcinoma; acc; carcinoma hypercortisolism; endocrinology ... See more keywords
Multiple concomitant life-threatening opportunistic infections due to uncontrolled hypercortisolism
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DOI: 10.1016/j.idcr.2022.e01420
Abstract: Opportunistic infections associated with severe cortisol excess carry a high mortality rate and are most prevalent with ectopic ACTH syndrome. There are limited reports of these cases described in the literature. In this case report,… read more here.
Keywords: opportunistic infections; infections due; hypercortisolism; threatening opportunistic ... See more keywords
Detrimental effects of hypercortisolism on brain structure and related risk factors
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DOI: 10.1038/s41598-020-68166-0
Abstract: Brain structural abnormalities are often observed on magnetic resonance imaging (MRI) scans of Cushing's syndrome patients, but the pathogenesis is not fully understood. To understand the relationship between brain structural abnormalities and potential risk factors… read more here.
Keywords: risk factors; detrimental effects; hypercortisolism; atrophy ... See more keywords
Diagnosis of naturally occurring canine hypercortisolism: survey of Australian veterinarians.
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DOI: 10.1111/avj.70033
Abstract: Naturally occurring hypercortisolism in dogs is commonly investigated in primary care practice. However, there is a poor understanding of the preference and interpretation of diagnostic tests by Australian veterinarians. This study aimed to investigate the… read more here.
Keywords: primary care; naturally occurring; survey; clinical signs ... See more keywords
Medical management of Cushing's disease: When and how?
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DOI: 10.1111/jne.13120
Abstract: Transsphenoidal surgery is the first‐line treatment of Cushing's disease. However, medical treatment can be given in a high proportion of patients with this rare condition. This is especially the case in severe hypercortisolism for which… read more here.
Keywords: hypercortisolism; medical management; treatment given; treatment ... See more keywords
Effect of pituitary-dependent hypercortisolism on the survival of dogs treated with radiotherapy for pituitary macroadenomas.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of veterinary internal medicine"
DOI: 10.1111/jvim.16724
Abstract: BACKGROUND Radiotherapy (RT) is an effective treatment for dogs presented with neurologic signs caused by pituitary tumors. However, its impact on the outcome of concurrent pituitary-dependent hypercortisolism (PDH) is controversial. OBJECTIVES Determine whether dogs with… read more here.
Keywords: hypercortisolism; pituitary dependent; pituitary macroadenomas; dependent hypercortisolism ... See more keywords