Action potential initiation, propagation, and cortical invasion in the hyperdirect pathway during subthalamic deep brain stimulation
Sign Up to like & getrecommendations! Published in 2018 at "Brain Stimulation"
DOI: 10.1016/j.brs.2018.05.008
Abstract: BACKGROUND High frequency (∼130 Hz) deep brain stimulation (DBS) of the subthalamic region is an established clinical therapy for the treatment of late stage Parkinson's disease (PD). Direct modulation of the hyperdirect pathway, defined as cortical… read more here.
Keywords: propagation; stimulation; hyperdirect pathway; hyperdirect ... See more keywords
Subthalamic Deep Brain Stimulation of an Anatomically Detailed Model of the Human Hyperdirect Pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neurophysiology"
DOI: 10.1152/jn.00004.2022
Abstract: The motor hyperdirect pathway (HDP) is considered a key target in the treatment of Parkinson's disease with subthalamic deep brain stimulation (DBS). This hypothesis is partially derived from the association of HDP activation with evoked… read more here.
Keywords: hyperdirect pathway; subthalamic deep; deep brain; stimulation ... See more keywords
Probabilistic versus deterministic tractography for delineation of the cortico-subthalamic hyperdirect pathway in patients with Parkinson disease selected for deep brain stimulation.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of neurosurgery"
DOI: 10.3171/2016.4.jns1624
Abstract: OBJECTIVE Diffusion-weighted MRI (DWI) and tractography allows noninvasive mapping of the structural connections of the brain, and may provide important information for neurosurgical planning. The hyperdirect pathway, connecting the subthalamic nucleus (STN) with the motor… read more here.
Keywords: tractography; patients parkinson; hyperdirect pathway; method ... See more keywords
Insights into the Glutamatergic and GABAergic Connections in the Conductance-Based Model of Subthalamic Nucleus in Hyperdirect Pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Neurology India"
DOI: 10.4103/0028-3886.375435
Abstract: Introduction This study aimed to analyze the spiking patterns of subthalamic nucleus and globus pallidus coupling in hyperdirect pathway in healthy primates and in Parkinson's disease using a conductance-based model. The effect of calcium membrane… read more here.
Keywords: hyperdirect pathway; subthalamic nucleus; conductance based; based model ... See more keywords