Thromboelastometric Profile and Acute Coagulopathy of the Polytraumatized Patient: Clinical and Prognostic Implications.
Sign Up to like & getrecommendations! Published in 2018 at "Cirugia Espanola"
DOI: 10.1016/j.cireng.2017.09.012
Abstract: Abstract Introduction About 25%–35% of polytraumatized patients have a profound alteration of hemostasis on arrival at the hospital (acute traumatic coagulopathy [CAT]). Viscoelastic tests (ROTEM®) measure the hemostatic capacity and provide an early detection of… read more here.
Keywords: acute; hyperfibrinolysis; blood; cat ... See more keywords
Association between ascites and primary hyperfibrinolysis: A cohort study in 210 dogs.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary journal"
DOI: 10.1016/j.tvjl.2017.03.008
Abstract: Coagulation profiles were determined in 70 dogs with ascites, 70 healthy control dogs and 70 sick control dogs without ascites. Dogs with ascites were divided into four sub-groups based on the pathophysiology of fluid formation.… read more here.
Keywords: primary hyperfibrinolysis; plasma; control; hyperfibrinolysis ... See more keywords
Fibrinolytic shutdown diagnosed with rotational thromboelastometry represents a moderate form of coagulopathy associated with transfusion requirement and mortality: A retrospective analysis.
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Anaesthesiology"
DOI: 10.1097/eja.0000000000001096
Abstract: BACKGROUND Viscoelastic techniques have made it possible to describe specific fibrinolytic phenotypes (physiological, hyperfibrinolysis and shutdown) and to establish a relationship of these phenotypes with outcome. However, there remains a debate as to whether shutdown… read more here.
Keywords: rotational thromboelastometry; shutdown; hyperfibrinolysis; mortality ... See more keywords
Hyperfibrinolysis secondary to acquired factor XIII deficiency A case report
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DOI: 10.1097/md.0000000000029446
Abstract: Introduction: Hyperfibrinolysis induced by factor XIII deficiency (FXIIID) is extremely rare, and patients with no manifestations of active bleeding can easily and frequently be neglected in clinical practice, leading to a missed diagnosis. Herein, we… read more here.
Keywords: factor xiii; factor; hyperfibrinolysis; xiii deficiency ... See more keywords
Plasmin TEG Rapidly Identifies Trauma Patients at Risk for Massive Transfusion, Mortality and Hyperfibrinolysis: A Diagnostic Tool to Resolve an International Debate on TXA?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000002941
Abstract: BACKGROUND Trauma patients with hyperfibrinolysis and depletion of fibrinolytic inhibitors(DFI) measured by thrombelastography(TEG) gain clot strength with TXA, but TEG results take nearly an hour. We aimed to develop an assay, plasmin TEG(P-TEG), to more… read more here.
Keywords: time; teg; plasmin; trauma patients ... See more keywords
Plasma-based assays distinguish hyperfibrinolysis and shutdown subgroups in trauma-induced coagulopathy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000003723
Abstract: Trauma patients with spontaneous #clot breakdown (fibrinolysis) have increased death and disability. We detected abnormal fibrin formation and structure in plasmas from these patients. These differences reveal mechanisms that may promote poor outcomes in #trauma.… read more here.
Keywords: thrombin generation; trauma; hyperfibrinolysis shutdown; generation ... See more keywords
Lysis Timer: a new sensitive tool to diagnose hyperfibrinolysis in liver transplantation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2018-205280
Abstract: Aims Diagnosis of hyperfibrinolysis in orthotopic liver transplantation (OLT) remains challenging. Euglobulin clot lysis time (ECLT) is not adapted to clinical situations. ROTEM is specific but seldom sensitive to hyperfibrinolysis. The Lysis Timer assesses ‘Global… read more here.
Keywords: lysis; liver transplantation; lysis timer; hyperfibrinolysis ... See more keywords
Enhanced fibrinolysis detection in a natural occurring canine model with intracavitary effusions: Comparison and degree of agreement between thromboelastometry and FDPs, D-dimer and fibrinogen concentrations
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0225089
Abstract: Dogs with intracavitary effusion have coagulative abnormalities indicative of primary fibrinolysis/hyperfibrinolysis. The aim of this case control study was to investigate by rotational thromboelastometry (ROTEM) and standard coagulation tests (fibrin-fibrinogen degradation products, D-dimer and fibrinogen)… read more here.
Keywords: standard coagulation; fibrinolysis; hyperfibrinolysis; dogs intracavitary ... See more keywords