MAFLD and glomerular hyperfiltration in subjects with normoglycemia, prediabetes and type 2 diabetes: A cross‐sectional population study
Sign Up to like & getrecommendations! Published in 2024 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3810
Abstract: Metabolic dysfunction‐associated fatty liver disease (MAFLD, 2020 diagnostic criteria) and glomerular hyperfiltration share common risk factors, including obesity, insulin resistance, impaired glucose tolerance, diabetes, dyslipidemia, and hypertension. read more here.
Keywords: subjects normoglycemia; hyperfiltration; mafld glomerular; normoglycemia prediabetes ... See more keywords
Erratum to: Characterisation of glomerular haemodynamic responses to SGLT2 inhibition in patients with type 1 diabetes and renal hyperfiltration
Sign Up to like & getrecommendations! Published in 2017 at "Diabetologia"
DOI: 10.1007/s00125-017-4241-3
Abstract: The authors wish to point out a typographical error in the penultimate paragraph of this research letter. The second main observation of the research was that treatment with empagliflozin for 8 weeks increased RA (not… read more here.
Keywords: responses sglt2; glomerular haemodynamic; erratum characterisation; characterisation glomerular ... See more keywords
Pre-Transplant Glomerular Hyperfiltration Is Not Associated with Renal Morbidity or Overall Mortality in Pediatric Patients
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2019.12.650
Abstract: Introduction Glomerular hyperfiltration is defined as an abnormally high GFR. Consensus is lacking as to what GFR constitutes hyperfiltration, and its role as a risk factor for acute kidney injury (AKI) and chronic kidney disease… read more here.
Keywords: gfr; pre transplant; hyperfiltration; renal morbidity ... See more keywords
Glomerular hyperfiltration is a predictor of adverse cardiovascular outcomes.
Sign Up to like & getrecommendations! Published in 2018 at "Kidney international"
DOI: 10.1016/j.kint.2017.07.013
Abstract: The association between glomerular hyperfiltration and cardiovascular events is not well known. To investigate whether glomerular hyperfiltration is independently associated with risk of adverse outcome we analyzed 8794 participants, average age 52 years enrolled in… read more here.
Keywords: normal egfr; predictor; cardiovascular events; hyperfiltration ... See more keywords
Hyperfiltration in ubiquitin C-terminal hydrolase L1-deleted mice.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical science"
DOI: 10.1042/cs20180085
Abstract: Neuronal ubiquitin C-terminal hydrolase L1 (UCHL1) is a deubiquitinating enzyme that maintains intracellular ubiquitin pools and promotes axonal transport. Uchl1 deletion in mice leads to progressive axonal degeneration, affecting the dorsal root ganglion that harbors… read more here.
Keywords: terminal hydrolase; ubiquitin terminal; mice; uchl1 mice ... See more keywords
P5463Hyperfiltration could be a risk factor for development of hypertension: A five-year cohort study
Sign Up to like & getrecommendations! Published in 2019 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehz746.0418
Abstract: Some recent studies showed that hyperfiltration is a risk for cardiovascular disease. However, the mechanism is still unknown. This longitudinal study tested the hypothesis that hyperfiltration could be a risk for hypertension. This study retrospectively… read more here.
Keywords: risk; development hypertension; study; hypertension ... See more keywords
Glomerular hyperfiltration as a therapeutic target for CKD
Sign Up to like & getrecommendations! Published in 2024 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfae027
Abstract: ABSTRACT The global burden of chronic kidney disease (CKD) is high and increasing. Early diagnosis and intervention are key to improve outcomes. Single-nephron glomerular hyperfiltration is an early pathophysiologic manifestation of CKD that may result… read more here.
Keywords: ckd; loss; hyperfiltration; kidney disease ... See more keywords
AUGMENTED PROSTAGLANDIN E2 SIGNALING CAUSES PODOCYTE DAMAGE AND ALBUMINURIA-LIKE PHENOTYPE IN A ZEBRAFISH DISEASE MODEL OF GLOMERULAR HYPERFILTRATION
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000835672.75347.e7
Abstract: Objective: Prostaglandins (PGs) are important active lipids synthesized from arachidonic acid with the participation of cyclooxygenases (COXs) and specific prostaglandin synthases. Prostaglandin E2 (PGE2), the most abundant prostaglandin in the kidney, plays a crucial role… read more here.
Keywords: albuminuria like; microscopy; glomerular hyperfiltration; hyperfiltration ... See more keywords
CANAGLIFLOZIN IS MORE EFFECTIVE THAN PERINDOPRIL TO IMPROVE RENAL HYPERFILTRATION AND URINARY ALBUMIN EXCRETION IN TYPE 2 DIABETES PATIENTS
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000837308.44611.23
Abstract: Objective: Introduction: Albumin urinary excretion and glomerular hyperfiltration is frequently found in diabetes and hypertension. Although converting enzyme inhibitors and iSGLT2 could stabilize renal function in long term trials, short information was available in comparative… read more here.
Keywords: hyperfiltration; type; excretion; perindopril ... See more keywords
Novel insights in classic versus relative glomerular hyperfiltration and implications on pharmacotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Nephrology and Hypertension"
DOI: 10.1097/mnh.0000000000000847
Abstract: Purpose of review Glomerular filtration rate (GFR) assessment and its estimation (eGFR) is a long-lasting challenge in medicine and public health. Current eGFR formulae are indexed for standardized body surface area (BSA) of 1.73 m2, ignoring… read more here.
Keywords: versus relative; glomerular hyperfiltration; classic versus; hyperfiltration ... See more keywords
Enuresis and Hyperfiltration in Children With Sickle Cell Disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000002426
Abstract: Nocturnal enuresis is a common symptom in children with sickle cell disease (SCD). Risk factors for development of enuresis are currently unknown. An early manifestation of SCD-associated kidney damage is glomerular hyperfiltration. We test the… read more here.
Keywords: enuresis; hyperfiltration; cell disease; sickle cell ... See more keywords