Hyperforin protects against acute cerebral ischemic injury through inhibition of interleukin-17A-mediated microglial activation
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DOI: 10.1016/j.brainres.2017.08.023
Abstract: Hyperforin, a pharmacologically active component of the medicinal plant Hypericum perforatum (St. John's wort), has been shown to be neuroprotective against acute ischemic stroke. However, the underlying mechanisms are still unclear and need to be… read more here.
Keywords: acute cerebral; interleukin 17a; activation; injury ... See more keywords
Downstream processing of hyperforin from Hypericum perforatum root cultures
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DOI: 10.1016/j.ejpb.2017.06.026
Abstract: Graphical abstract Figure. No Caption available. ABSTRACT Hyperforin is a major metabolite of the medicinal plant Hypericum perforatum (St. John’s Wort) and has recently been found in hormone induced root cultures. The objective of this… read more here.
Keywords: hypericum perforatum; extraction; root cultures; hyperforin ... See more keywords
Abstract 4874: Hyperforin induces apoptosis and inhibits invasion via inhibiting AKT/NF-ΚB signaling pathway in colorectal cancer cells
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DOI: 10.1158/1538-7445.am2023-4874
Abstract: Recently, the incidence of colorectal cancer (CRC) has been increasing year by year and has become the first incidence cancer in Taiwan. Epidermal growth factor receptor inhibitor (EGFR inhibitor) has been recognized as an important… read more here.
Keywords: akt signaling; crc; colorectal cancer; inhibiting akt ... See more keywords