Comparison of stress hyperglycemia ratio and glycemic gap on acute ICH in‐hospital outcomes
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.52063
Abstract: To compare the effect of different indicators on stress‐induced hyperglycemia for predicting in‐hospital outcomes of acute intracerebral hemorrhage. read more here.
Keywords: comparison stress; hyperglycemia ratio; stress hyperglycemia; hyperglycemia ... See more keywords
Coordination of Functional Oligonucleotides Yields a Versatile Nanocomposite Microneedle Patch to Facilitate Local Wound Microenvironment Remodeling via Systemic Hyperglycemia Regulation
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202423012
Abstract: Hyperglycemia exacerbates bacterial infections, disrupts angiogenesis, and perpetuates chronic inflammation in the wound. Therefore, the effective management of diabetic wounds necessitates a synergistic approach that integrates local wound microenvironment remodeling with systemic hyperglycemia regulation. Herein,… read more here.
Keywords: wound microenvironment; local wound; wound; hyperglycemia ... See more keywords
A Novel Therapeutic Strategy for Ameliorating Hyperglycemia-Induced Liver Injury via Overexpression of the Carboxyl Terminus of HSP70-Interacting Protein in Wharton's Jelly Mesenchymal Stem Cells.
Sign Up to like & getrecommendations! Published in 2025 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2771
Abstract: Diabetes is a widespread metabolic disorder that significantly affects modern society. The liver plays a vital role in metabolism; however, hyperglycemia can induce liver damage and disrupt its normal functions. Wharton's jelly mesenchymal stem cells… read more here.
Keywords: stem cells; injury; chip; hyperglycemia ... See more keywords
Risk factors and clinical implications of hyperglycemia during induction therapy in pediatric acute lymphoblastic leukemia
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DOI: 10.1002/ijc.70084
Abstract: Hyperglycemia during induction therapy in adult acute lymphoblastic leukemia (ALL) is associated with adverse outcomes, yet its impact in pediatric ALL remains incompletely understood. This study aimed to determine the incidence of hyperglycemia in pediatric… read more here.
Keywords: hyperglycemia; induction therapy; risk factors; induction ... See more keywords
Hesperetin‐loaded chitosan nanoparticles ameliorate hyperglycemia by regulating key enzymes of carbohydrate metabolism in a diabetic rat model
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23805
Abstract: The study aimed to investigate the potential of hesperetin‐loaded chitosan nanoparticles (HSPCNPs) in alleviating hyperglycemia by modulating key enzymes in diabetic rats. Chitosan nanoparticles loaded with hesperetin were prepared using the ionic gelation method and… read more here.
Keywords: chitosan nanoparticles; hesperetin loaded; hyperglycemia; carbohydrate metabolism ... See more keywords
Hyperglycemia‐Triggered Sphingosine‐1‐Phosphate and Sphingosine‐1‐Phosphate Receptor 3 Signaling Worsens Liver Ischemia/Reperfusion Injury by Regulating M1/M2 Polarization
Sign Up to like & getrecommendations! Published in 2019 at "Liver Transplantation"
DOI: 10.1002/lt.25470
Abstract: Hyperglycemia aggravates hepatic ischemia/reperfusion injury (IRI), but the underlying mechanism for the aggravation remains elusive. Sphingosine‐1‐phosphate (S1P) and sphingosine‐1‐phosphate receptors (S1PRs) have been implicated in metabolic and inflammatory diseases. Here, we discuss whether and how… read more here.
Keywords: polarization; ischemia reperfusion; hyperglycemia; sphingosine phosphate ... See more keywords
Hypoxia-inducible factor 1α protects peripheral sensory neurons from diabetic peripheral neuropathy by suppressing accumulation of reactive oxygen species.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-018-1707-9
Abstract: Diabetic peripheral neuropathy (DPN) is one of the most common diabetic complications. Mechanisms underlying nerve damage and sensory loss following metabolic dysfunction remain largely unclear. Recently, hyperglycemia-induced mitochondrial dysfunction and the generation of reactive oxygen… read more here.
Keywords: inducible factor; hif1; sensory neurons; hyperglycemia ... See more keywords
Improvement in Hyperglycemia Prevents Surgical Site Infection Irrespective of Insulin Therapy in Non-diabetic Patients Undergoing Gastrointestinal Surgery
Sign Up to like & getrecommendations! Published in 2020 at "World Journal of Surgery"
DOI: 10.1007/s00268-020-05371-y
Abstract: Background Intensive glycemic control is recommended to prevent surgical site infections (SSI). Our aim was to evaluate retrospectively the effect of improvement in hyperglycemia irrespective of insulin use on the incidence of SSI in non-diabetic… read more here.
Keywords: surgery; insulin therapy; diabetic patients; hyperglycemia ... See more keywords
Trajectories of energy intake distribution and subsequent risk of hyperglycemia among Chinese adults: findings from the China Health and Nutrition Survey (1997–2018)
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DOI: 10.1007/s00394-021-02745-3
Abstract: Few studies have examined the secular trend of the energy intake distribution, and its effect on future risk of hyperglycemia. This study aims to describe trajectories of energy intake distribution over 12 years and relate… read more here.
Keywords: risk; energy intake; energy; group ... See more keywords
Hyperglycemia regulates cardiac K+ channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways
Sign Up to like & getrecommendations! Published in 2020 at "Basic Research in Cardiology"
DOI: 10.1007/s00395-020-00834-8
Abstract: Chronic hyperglycemia and diabetes lead to impaired cardiac repolarization, K+ channel remodeling and increased arrhythmia risk. However, the exact signaling mechanism by which diabetic hyperglycemia regulates cardiac K+ channels remains elusive. Here, we show that… read more here.
Keywords: nox2 ros; hyperglycemia regulates; camkii; hyperglycemia ... See more keywords
Endothelium-dependent vasodilation in the cerebral arterioles of rats deteriorates during acute hyperglycemia and then is restored by reducing the glucose level
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Anesthesia"
DOI: 10.1007/s00540-018-2507-7
Abstract: PurposeAcute hyperglycemia in patients with traumatic brain injury correlates with a poor neurological outcome. We investigated the endothelium function of rat cerebral arterioles during acute hyperglycemia and after reducing the glucose levels using insulin. We… read more here.
Keywords: endothelium; reducing glucose; cerebral arterioles; hyperglycemia ... See more keywords