KLF9 regulates PRDX6 expression in hyperglycemia-aggravated bupivacaine neurotoxicity.
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DOI: 10.1007/s11010-021-04059-8
Abstract: BACKGROUND Neurotoxicity induced by local anesthetics (LAs) is potentially life threatening, especially for patients with underlying diseases like diabetes. The anesthetic bupivacaine (Bup) has been reported to induce neurotoxicity mediated by reactive oxygen species (ROS),… read more here.
Keywords: klf9 regulates; hyperglycemia aggravated; expression; neurotoxicity ... See more keywords
BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate
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DOI: 10.3390/ijms22179263
Abstract: Vascular calcification associated with high plasma phosphate (Pi) level is a frequent complication of hyperglycemia, diabetes mellitus, and chronic kidney disease. BGP-15 is an emerging anti-diabetic drug candidate. This study was aimed to explore whether… read more here.
Keywords: vsmc calcification; bgp; calcification; inhibits hyperglycemia ... See more keywords