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Hyperglycemia regulates cardiac K+ channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways

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1 Published in 2020 at "Basic Research in Cardiology"

DOI: 10.1007/s00395-020-00834-8

Abstract: Chronic hyperglycemia and diabetes lead to impaired cardiac repolarization, K+ channel remodeling and increased arrhythmia risk. However, the exact signaling mechanism by which diabetic hyperglycemia regulates cardiac K+ channels remains elusive. Here, we show that… read more here.

Keywords: nox2 ros; hyperglycemia regulates; camkii; hyperglycemia ... See more keywords