Prevalence and clinical demography of hyperhomocysteinemia in Han Chinese patients with schizophrenia
Sign Up to like & getrecommendations! Published in 2020 at "European Archives of Psychiatry and Clinical Neuroscience"
DOI: 10.1007/s00406-020-01150-x
Abstract: Previous studies have shown that high homocysteine worsens the occurrence, symptoms, and prognosis of patients with schizophrenia. The purpose of this study was to evaluate the prevalence, clinical correlation, and demographic characteristics of hyperhomocysteinemia in… read more here.
Keywords: patients schizophrenia; prevalence; han chinese; hyperhomocysteinemia ... See more keywords
Hyperhomocysteinemia and cardiovascular disease in animal model
Sign Up to like & getrecommendations! Published in 2017 at "Amino Acids"
DOI: 10.1007/s00726-017-2503-5
Abstract: Hyperhomocysteinemia is an independent risk factor for cardiovascular disease and is associated with primary causes of mortality and morbidity throughout the world. Several studies have been carried out to evaluate the effects of a diet… read more here.
Keywords: animal model; homocysteine; disease; hyperhomocysteinemia ... See more keywords
CBS mutations and MTFHR SNPs causative of hyperhomocysteinemia in Pakistani children
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology Reports"
DOI: 10.1007/s11033-018-4169-9
Abstract: Three index patients with hyperhomocysteinemia and ocular anomalies were screened for cystathionine beta synthase (CBS) and methylenetetrahydrofolate reductase (MTHFR) polymorphisms. Genotyping of hyperhomocysteinemia associated MTHFR polymorphisms C677T (rs1801133) and A1298C (rs1801131) was done by PCR-restriction… read more here.
Keywords: mthfr polymorphisms; cbs mutations; mtfhr snps; mutations mtfhr ... See more keywords
Is hyperhomocysteinemia a causal factor for heart failure? The impact of the functional variants of MTHFR and PON1 on ischemic and non-ischemic etiology.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of cardiology"
DOI: 10.1016/j.ijcard.2016.11.213
Abstract: BACKGROUND Hyperhomocysteinemia was found to be uniformly associated with the development of heart failure (HF) and HF mortality; however, it is uncertain whether this relation is causative or not. We used Mendelian randomization to examine… read more here.
Keywords: ischemic etiology; etiology; hyperhomocysteinemia causal; heart failure ... See more keywords
Calcium sensing receptor initiating cystathionine‐gamma‐lyase/hydrogen sulfide pathway to inhibit platelet activation in hyperhomocysteinemia rat
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2017.06.013
Abstract: ABSTRACT Hyperhomocysteinemia (HHcy, high homocysteine) induces the injury of endothelial cells (ECs). Hydrogen sulfide (H2S) protects ECs and inhibits the activation of platelets. Calcium‐sensing receptor (CaSR) regulates the production of endogenous H2S. However, whether CaSR… read more here.
Keywords: activation; hyperhomocysteinemia; receptor; hydrogen sulfide ... See more keywords
Hydrogen Sulfide Protects Hyperhomocysteinemia-Induced Renal Damage by Modulation of Caveolin and eNOS Interaction
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-018-38467-6
Abstract: The accumulation of homocysteine (Hcy) during chronic kidney failure (CKD) can exert toxic effects on the glomeruli and tubulo-interstitial region. Among the potential mechanisms, the formation of highly reactive metabolite, Hcy thiolactone, is known to… read more here.
Keywords: hhcy; caveolin; hyperhomocysteinemia; hydrogen sulfide ... See more keywords
Hyperhomocysteinemia in Cardiovascular Diseases: Revisiting Observational Studies and Clinical Trials
Sign Up to like & getrecommendations! Published in 2022 at "Thrombosis and Haemostasis"
DOI: 10.1055/a-1952-1946
Abstract: Thromboembolic manifestations are relativement frequent in patients with intermediate/severe hyperhomocysteinemia (> 30 µmol/L) related to inherited disorders and deficiencies in vitamin B12 and folate. In contrast, moderate hyperhomocysteinemia (15- 30 µmol/L) is a modest predictor… read more here.
Keywords: revisiting observational; clinical trials; observational studies; studies clinical ... See more keywords
Mild Hyperhomocysteinemia Induced by a Hypomethylating Diet Does Not Favor Aortic Plaque Formation in apoE Knockout Mice (P24-037-19).
Sign Up to like & getrecommendations! Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz044.p24-037-19
Abstract: Objectives Hyperhomocysteinemia is an independent risk factor for atherosclerosis and cardiovascular disease through mechanisms still incompletely defined. We investigated the impact of mild diet-induced accumulation of homocysteine on atherosclerotic plaque formation in apoE knockout (KO)… read more here.
Keywords: mice; plaque; hyperhomocysteinemia; apoe ... See more keywords
Microglial-associated responses to comorbid amyloid pathology and hyperhomocysteinemia in an aged knock-in mouse model of Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-020-01938-7
Abstract: Background Elevated blood homocysteine levels, termed hyperhomocysteinemia (HHcy), is a prevalent risk factor for Alzheimer’s disease (AD) in elderly populations. While dietary supplementation of B-vitamins is a generally effective method to lower homocysteine levels, there… read more here.
Keywords: alzheimer disease; pathology; knock mouse; hyperhomocysteinemia ... See more keywords
Acute coronary syndrome with large thrombus successfully managed with no-stenting revascularization based on intravascular imaging in a patient with hyperhomocysteinemia: a case report
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DOI: 10.1186/s13256-020-02531-5
Abstract: Background Hyperhomocysteinemia is caused by genetic and environmental factors, which can result in systemic arteriosclerosis and arteriovenous thrombosis including acute coronary syndrome. Thrombus burden in patients with acute coronary syndrome and hyperhomocysteinemia might involve the… read more here.
Keywords: acute coronary; spectroscopy; hyperhomocysteinemia; coronary syndrome ... See more keywords
Hyperhomocysteinemia and pregnancy outcomes in women with polycystic ovary syndrome: A case-control study
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Reproductive Biomedicine"
DOI: 10.18502/ijrm.v21i2.12807
Abstract: Abstract Background One of the reproductive medicine challenges is to determine the role of hyperhomocysteinemia in the pathogenesis of polycystic ovary syndrome (PCOS), especially in women with recurrent pregnancy loss (RPL). Objective Determine the correlation… read more here.
Keywords: level; group; pregnancy; hyperhomocysteinemia ... See more keywords