State of antioxidant systems and phenolic compounds’ production in Hypericum perforatum L. hairy roots
Sign Up to like & getrecommendations! Published in 2019 at "Acta Physiologiae Plantarum"
DOI: 10.1007/s11738-019-2919-5
Abstract: Hypericum perforatum hairy root clones (HR A–HR O) transformed with Agrobacterium rhizogenes A4 were evaluated for growth characteristics, phenolic compounds production, antioxidant/radical scavenging activity, antioxidant enzymes, and oxidative stress markers. The screening of growth characteristics… read more here.
Keywords: production; compounds production; perforatum hairy; phenolic compounds ... See more keywords
Trace Element Uptake and Accumulation in the Medicinal Herb Hypericum perforatum L. Across Different Geolithological Settings
Sign Up to like & getrecommendations! Published in 2018 at "Biological Trace Element Research"
DOI: 10.1007/s12011-018-1453-4
Abstract: The worldwide growing interest in traditional medicines, including herbal medicines and herbal dietary supplements, has recently been accompanied by concerns on quality and safety of this type of health care. The content of nutritional and… read more here.
Keywords: medicinal herb; perforatum; herb hypericum; hypericum perforatum ... See more keywords
In Vitro Regeneration and Free Radical Scavenging Assay of Hypericum perforatum L.
Sign Up to like & getrecommendations! Published in 2019 at "National Academy Science Letters"
DOI: 10.1007/s40009-018-0699-x
Abstract: Abstract The phytochemistry of Hypericum perforatum (St. John’s wort) has been elaborated extensively owing to its immense application in medicinal chemistry. Most of pharmacological activities were assigned to presence of photosensitive naphthodianthrone, hypericin and other… read more here.
Keywords: hypericum perforatum; scavenging assay; radical scavenging; free radical ... See more keywords
Downstream processing of hyperforin from Hypericum perforatum root cultures
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2017.06.026
Abstract: Graphical abstract Figure. No Caption available. ABSTRACT Hyperforin is a major metabolite of the medicinal plant Hypericum perforatum (St. John’s Wort) and has recently been found in hormone induced root cultures. The objective of this… read more here.
Keywords: hypericum perforatum; extraction; root cultures; hyperforin ... See more keywords
Effects of nitrogen substitute and Hypericum perforatum extract on the ethanol fermentation of traditional Chinese medicine dregs
Sign Up to like & getrecommendations! Published in 2019 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2018.11.021
Abstract: Abstract Hypericum perforatum residue waste, which is obtained after the extraction of a traditional Chinese herbal medicine, contained a high concentration of cellulose that can be used for ethanol production. The addition of other wastes… read more here.
Keywords: medicine; hypericum perforatum; dregs; ethanol fermentation ... See more keywords
Hyperforatins L-U: Prenylated acylphloroglucinols with a terminal double bond from Hypericum perforatum L. (St John's Wort).
Sign Up to like & getrecommendations! Published in 2019 at "Phytochemistry"
DOI: 10.1016/j.phytochem.2019.04.011
Abstract: Hyperforatins L-U, ten undescribed polycyclic polyprenylated acylphloroglucinols (PPAPs) bearing a terminal double bond, together with a known compound hypericumoxide J, were isolated from the aerial parts of Hypericum perforatum L. Their structures were elucidated by… read more here.
Keywords: hypericum perforatum; terminal double; double bond; hyperforatins prenylated ... See more keywords
Additional Insights into Hypericum perforatum Content: Isolation, Total Synthesis, and Absolute Configuration of Hyperbiphenyls A and B from Immunomodulatory Root Extracts.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.8b00325
Abstract: Phytochemical investigation of the root extracts of Hypericum perforatum led to the isolation of two biphenyl derivatives named hyperbiphenyls A and B (1 and 2) and four known xanthones (3-6). These structures were elucidated by… read more here.
Keywords: hypericum perforatum; total synthesis; absolute configuration; root extracts ... See more keywords
Identification of Major Constituents of Hypericum perforatum L. Extracts in Syria by Development of a Rapid, Simple, and Reproducible HPLC-ESI-Q-TOF MS Analysis and Their Antioxidant Activities
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.1c06335
Abstract: Hypericum perforatum Linn (St. John’s wort) is a popular and widespread medicine in Syria, which is used for a wide range of conditions, including gastrointestinal diseases, heart disease, skin diseases, and psychological disorders. This widespread… read more here.
Keywords: using different; identification major; hypericum perforatum; different solvents ... See more keywords
The Petroleum Ether Extract from Hypericum perforatum Root Cultures Exhibits Potent Antiproliferative Activity in Human Keratinocytes and Fibroblasts.
Sign Up to like & getrecommendations! Published in 2019 at "Planta medica"
DOI: 10.1055/a-0806-7735
Abstract: The hyperforin content of Hypericum perforatum herb was repeatedly reported to be responsible for a multitude of pharmacological activities. Our recent report about the hyperforin accumulation in in vitro root cultures of H. perforatum provides… read more here.
Keywords: hypericum perforatum; root cultures; root; antiproliferative activity ... See more keywords
Biosynthesis of polyprenylated xanthones in Hypericum perforatum roots involves 4-prenyltransferase.
Sign Up to like & getrecommendations! Published in 2023 at "Plant physiology"
DOI: 10.1093/plphys/kiad219
Abstract: Polyprenylated xanthones are natural products with a multitude of biological and pharmacological activities. However, their biosynthetic pathway is not completely understood. In this study, metabolic profiling revealed the presence of 4-prenylated 1,3,5,6-tetrahydroxyxanthone derivatives in St.… read more here.
Keywords: tetrahydroxyxanthone; hypericum perforatum; hppt4px hppt4px; hppt4px ... See more keywords
Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans
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DOI: 10.1111/bcp.14553
Abstract: To investigate the influence of a cytochrome P450 CYP3A4 and efflux transporter P‐glycoprotein (P‐gp) inducing Hypericum perforatum extract on the pharmacokinetics and pharmacodynamics of rivaroxaban. read more here.
Keywords: pharmacodynamics rivaroxaban; effects hypericum; pharmacokinetics pharmacodynamics; hypericum perforatum ... See more keywords