Chronic glucocorticoid treatment induces hepatic lipid accumulation and hyperinsulinaemia in part through actions on AgRP neurons
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DOI: 10.1038/s41598-021-93378-3
Abstract: Glucocorticoids (GCs) are widely prescribed anti-inflammatory medicines, but their use can lead to metabolic side-effects. These may occur through direct actions of GCs on peripheral organs, but could also be mediated by the hypothalamic AgRP… read more here.
Keywords: part; treatment; agrp mice; cort ... See more keywords
Relationships between hyperinsulinaemia, magnesium, vitamin D, thrombosis and COVID-19: rationale for clinical management
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DOI: 10.1136/openhrt-2020-001356
Abstract: Risk factors for COVID-19 patients with poorer outcomes include pre-existing conditions: obesity, type 2 diabetes mellitus, cardiovascular disease (CVD), heart failure, hypertension, low oxygen saturation capacity, cancer, elevated: ferritin, C reactive protein (CRP) and D-dimer.… read more here.
Keywords: risk; magnesium vitamin; vitamin; thrombosis ... See more keywords
Can the Molar Insulin: C-Peptide Ratio Be Used to Predict Hyperinsulinaemia?
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DOI: 10.3390/biomedicines8050108
Abstract: Hyperinsulinaemia is the precursor to numerous metabolic disorders. Early diagnosis and intervention could improve population health. Diagnosing hyperinsulinaemia is problematic because insulin has a very short half-life (2–5 min). It is theorised that c-peptide levels… read more here.
Keywords: four hour; insulin; hyperinsulinaemia; correlation ... See more keywords