Hyperinsulinaemic hypoglycaemia in non-anaesthetized Göttingen minipigs induces a counter-regulatory endocrine response and electrocardiographic changes
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DOI: 10.1038/s41598-021-84758-w
Abstract: The potentially fatal cardiovascular effects of hypoglycaemia are not well understood and large animal models of the counter-regulatory responses and cardiovascular consequences of insulin-induced hypoglycaemia are needed to understand the mechanisms in humans. The aim… read more here.
Keywords: insulin; counter regulatory; hypoglycaemia; effects hypoglycaemia ... See more keywords
Hyperinsulinaemic hypoglycaemia: A new presentation of 16p11.2 deletion syndrome
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DOI: 10.1111/cen.13951
Abstract: 16p11.2 microdeletion syndrome is a recognisable chromosomal anomaly caused by microdeletions in the 16p11.2 locus. It is characterized by developmental delay intellectual disability and social impairments or susceptibility to autism spectrum disorder. It also involves… read more here.
Keywords: new presentation; hypoglycaemia new; hypoglycaemia; deletion ... See more keywords
Clinical and genetic heterogeneity of HNF4A/HNF1A mutations in a multicentre paediatric cohort with hyperinsulinaemic hypoglycaemia.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of endocrinology"
DOI: 10.1530/eje-21-0897
Abstract: Objective The phenotype mediated by HNF4A/HNF1A mutations is variable and includes diazoxide-responsive hyperinsulinaemic hypoglycaemia (HH) and maturity-onset diabetes of the young (MODY). Design We characterised an international multi-centre paediatric cohort of patients with HNF4A or… read more here.
Keywords: hnf4a hnf1a; clinical genetic; hnf1a mutations; paediatric cohort ... See more keywords