TNF, but not hyperinsulinemia or hyperglycemia, is a key driver of obesity‐induced monocytosis revealing that inflammatory monocytes correlate with insulin in obese male mice
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DOI: 10.14814/phy2.13937
Abstract: Inflammation contributes to obesity‐related hyperinsulinemia and insulin resistance, which often precede type 2 diabetes. Inflammation is one way that obesity can promote insulin resistance. It is not clear if the extent of obesity, hyperinsulinemia, or… read more here.
Keywords: insulin; mice; insulin resistance; obesity ... See more keywords
Interactive contribution of hyperinsulinemia, hyperglycemia, and mammalian target of rapamycin signaling to valvular interstitial cell differentiation and matrix remodeling
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DOI: 10.3389/fcvm.2022.942430
Abstract: Diabetes and its major key determinants insulin resistance and hyperglycemia are known risk factors for calcific aortic valve disease (CAVD). The processes leading to molecular and structural alterations of the aortic valve are yet not… read more here.
Keywords: hyperinsulinemia hyperglycemia; matrix remodeling; matrix; mtor ... See more keywords