Articles with "hyperlipidaemia" as a keyword



The pharmacokinetics of dabigatran in a rat model of hyperlipidaemia induced by poloxamer 407

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Published in 2024 at "Xenobiotica"

DOI: 10.1080/00498254.2024.2404168

Abstract: Abstract Various pharmacokinetic changes have been reported in experimental hyperlipidemic (HL) animal models. To evaluate whether P-glycoprotein (P-gp) activity was affected in HL rats, we assessed the pharmacokinetics of dabigatran after oral administration of dabigatran… read more here.

Keywords: pharmacokinetics dabigatran; hyperlipidaemia; rat model; control rats ... See more keywords

Regulating microsomal triglyceride transfer protein with natural products for the treatment of hyperlipidaemia

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Published in 2024 at "Natural Product Research"

DOI: 10.1080/14786419.2023.2300031

Abstract: Abstract Hyperlipidaemia, characterised by elevated levels of lipids, particularly LDL-C, is a significant risk factor for atherosclerotic cardiovascular disease. While synthetic inhibitors of microsomal triglyceride transfer protein (MTP) have shown potential in lowering LDL-C, they… read more here.

Keywords: transfer protein; natural products; triglyceride transfer; hyperlipidaemia ... See more keywords

Effects of hyperuricaemia, with the superposition of being overweight and hyperlipidaemia, on the incidence of acute kidney injury following cardiac surgery: a retrospective cohort study

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Published in 2022 at "BMJ Open"

DOI: 10.1136/bmjopen-2020-047090

Abstract: Objectives Acute kidney injury (AKI) is a common complication of cardiac surgery. This study aimed to explore the effects of hyperuricaemia, being overweight and hyperlipidaemia as risk factors for AKI in patients following cardiac surgery… read more here.

Keywords: hyperlipidaemia; acute kidney; overweight hyperlipidaemia; cardiac surgery ... See more keywords

Efficacy and safety of tai chi for hyperlipidaemia: a protocol for systematic review and meta-analysis

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Published in 2022 at "BMJ Open"

DOI: 10.1136/bmjopen-2021-053867

Abstract: Introduction The prevalence of hyperlipidaemia is increasing, and patients with hyperlipidaemia are at increased risk of cardiovascular disease and atherosclerosis. In recent years, there has been a growing number of studies on tai chi for… read more here.

Keywords: hyperlipidaemia; meta analysis; tai chi; efficacy safety ... See more keywords

Celecoxib exhibits therapeutic potential in experimental model of hyperlipidaemia

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Published in 2021 at "PLoS ONE"

DOI: 10.1371/journal.pone.0247735

Abstract: Hyperlipidaemia is a major risk factor for cardiovascular diseases, the leading cause of death globally. Celecoxib attenuated hypercholesterolaemia associated with CCl4-induced hepatic injury in rats without improving liver function in our previous study. This present… read more here.

Keywords: exhibits therapeutic; celecoxib; hyperlipidaemia; coconut oil ... See more keywords