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Published in 2024 at "Xenobiotica"
DOI: 10.1080/00498254.2024.2404168
Abstract: Abstract Various pharmacokinetic changes have been reported in experimental hyperlipidemic (HL) animal models. To evaluate whether P-glycoprotein (P-gp) activity was affected in HL rats, we assessed the pharmacokinetics of dabigatran after oral administration of dabigatran…
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Keywords:
pharmacokinetics dabigatran;
hyperlipidaemia;
rat model;
control rats ... See more keywords
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Published in 2024 at "Natural Product Research"
DOI: 10.1080/14786419.2023.2300031
Abstract: Abstract Hyperlipidaemia, characterised by elevated levels of lipids, particularly LDL-C, is a significant risk factor for atherosclerotic cardiovascular disease. While synthetic inhibitors of microsomal triglyceride transfer protein (MTP) have shown potential in lowering LDL-C, they…
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Keywords:
transfer protein;
natural products;
triglyceride transfer;
hyperlipidaemia ... See more keywords
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Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2020-047090
Abstract: Objectives Acute kidney injury (AKI) is a common complication of cardiac surgery. This study aimed to explore the effects of hyperuricaemia, being overweight and hyperlipidaemia as risk factors for AKI in patients following cardiac surgery…
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Keywords:
hyperlipidaemia;
acute kidney;
overweight hyperlipidaemia;
cardiac surgery ... See more keywords
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Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2021-053867
Abstract: Introduction The prevalence of hyperlipidaemia is increasing, and patients with hyperlipidaemia are at increased risk of cardiovascular disease and atherosclerosis. In recent years, there has been a growing number of studies on tai chi for…
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Keywords:
hyperlipidaemia;
meta analysis;
tai chi;
efficacy safety ... See more keywords
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Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0247735
Abstract: Hyperlipidaemia is a major risk factor for cardiovascular diseases, the leading cause of death globally. Celecoxib attenuated hypercholesterolaemia associated with CCl4-induced hepatic injury in rats without improving liver function in our previous study. This present…
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Keywords:
exhibits therapeutic;
celecoxib;
hyperlipidaemia;
coconut oil ... See more keywords