Hyperlipidaemia alone and in combination with acidosis can increase the incidence and severity of statin‐induced myotoxicity
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DOI: 10.1016/j.ejps.2017.01.018
Abstract: &NA; The association of lipophilic statins with plasma lipoproteins in the presence of disturbed acid‐base balance can modify the pharmacokinetics and tissue distribution of these drugs, resulting in alteration in their efficacy and toxicity profiles.… read more here.
Keywords: alone combination; hyperlipidaemia alone; myotoxicity; statin ... See more keywords