Multiple Enzymes Expressed by the Gut Microbiota Can Transform Typhaneoside and Are Associated with Improving Hyperlipidemia
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DOI: 10.1002/advs.202411770
Abstract: The mechanism of multiple enzymes mediated drug metabolism in gut microbiota is still unclear. This study explores multiple enzyme interaction process of typhactyloside (TYP) with gut microbiota and its lipid‐lowering pharmacological activity. TYP, with bioavailability… read more here.
Keywords: gut microbiota; multiple enzymes; hyperlipidemia; typ ... See more keywords
Hyperlipidemia induced metabolic changes in regulatory T cells result in altered function.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of immunology"
DOI: 10.1002/eji.202049149
Abstract: Regulatory T cells (Tregs) play a critical role in maintaining self-tolerance and controlling inflammation. However, physiologically relevant conditions that alter Treg function and drive disease pathogenesis are poorly understood and few have been defined. We… read more here.
Keywords: hyperlipidemia; metabolism; induction hyperlipidemia; regulatory cells ... See more keywords
Hyperuricemia Is Independently Associated With Hyperlipidemia in a Large Population-Based Study.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of clinical laboratory analysis"
DOI: 10.1002/jcla.70131
Abstract: Hyperlipidemia is a significant risk factor for cardiovascular diseases. Hyperuricemia has also been linked to adverse cardiometabolic outcomes, including dyslipidemia. The relationship between hyperuricemia and hyperlipidemia is of particular concern due to their combined impact… read more here.
Keywords: hyperuricemia; independently associated; associated hyperlipidemia; hyperlipidemia large ... See more keywords
Urinary metabolomics analysis of the protective effects of Daming capsule on hyperlipidemia rats using ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of separation science"
DOI: 10.1002/jssc.202100113
Abstract: Hyperlipidemia is recognized as one of the most important risk factors for morbidity and mortality due to cardiovascular diseases. Daming capsule, a Chinese patent medicine, has shown definitive efficacy in patients with hyperlipidemia. In this… read more here.
Keywords: hyperlipidemia; urinary metabolomics; capsule; daming capsule ... See more keywords
Hovenia Dulcis Extract Reduces Lipid Accumulation in Oleic Acid‐Induced Steatosis of Hep G2 Cells via Activation of AMPK and PPARα/CPT‐1 Pathway and in Acute Hyperlipidemia Mouse Model
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DOI: 10.1002/ptr.5741
Abstract: Hovenia dulcis Thunb. (HDT) was known to have anti‐fatigue, anti‐diabetes, neuroprotective, and hepatoprotective effects. In the present study, the anti‐fatty liver mechanism of HDT was elucidated in oleic acid (OA)‐treated Hep G2 cells and acute… read more here.
Keywords: hyperlipidemia; lipid accumulation; hep cells; acute hyperlipidemia ... See more keywords
Botanical Antinutrients as Natural Modulators of Postprandial Hyperglycemia and Hyperlipidemia: A Narrative Review
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DOI: 10.1002/ptr.70076
Abstract: Postprandial elevation in blood monosaccharide and lipid levels is recognized as a significant challenge to systemic homeostasis and physiology, which can be minimized by controlling and monitoring the use of antinutrients. Delve into the investigations… read more here.
Keywords: botanical antinutrients; hyperglycemia hyperlipidemia; hyperlipidemia; inhibitors obesity ... See more keywords
Sleep duration and risk of hyperlipidemia: a systematic review and meta-analysis of prospective studies
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DOI: 10.1007/s11325-021-02504-y
Abstract: Current studies indicate that the association between sleep duration and risk of hyperlipidemia is uncertain. This systematic review aimed to evaluate relevant prospective studies and make a definite conclusion. Three databases were searched for prospective… read more here.
Keywords: sleep duration; hyperlipidemia; duration; prospective studies ... See more keywords
Management of Hyperlipidemia After Stroke
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DOI: 10.1007/s11936-019-0774-8
Abstract: Hyperlipidemia is a key therapeutic target for stroke risk modification. The goal of this review is to highlight available treatment options and review their efficacy in the setting of general cardiovascular disease and after most… read more here.
Keywords: hyperlipidemia; risk; management hyperlipidemia; hyperlipidemia stroke ... See more keywords
Synergistic Cardioprotective Effects of Combined Chromium Picolinate and Atorvastatin Treatment in Triton X-100-Induced Hyperlipidemia in Rats: Impact on Some Biochemical Markers
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DOI: 10.1007/s12011-017-1010-6
Abstract: Hyperlipidemia is one of the major risk factors for atherosclerosis and ischemic heart disease. Chromium (Cr) mineral is playing a crucial role in glucose and lipid homeostasis. The aim of this study was to evaluate… read more here.
Keywords: hyperlipidemia; treatment; group; atorvastatin ... See more keywords
Discovery of a potent FKBP38 agonist that ameliorates HFD-induced hyperlipidemia via mTOR/P70S6K/SREBPs pathway
Sign Up to like & getrecommendations! Published in 2021 at "Acta Pharmaceutica Sinica B"
DOI: 10.1016/j.apsb.2021.03.031
Abstract: Abstract The mammalian target of rapamycin (mTOR)-sterol regulatory element-binding proteins (SREBPs) signaling promotes lipogenesis. However, mTOR inhibitors also displayed a significant side effect of hyperlipidemia. Thus, it is essential to develop mTOR-specific inhibitors to inhibit… read more here.
Keywords: srebps pathway; hyperlipidemia; p70s6k srebps; mtor ... See more keywords
Hypolipidemic Components from Medicine Food Homology Species Used in China: Pharmacological and Health Effects.
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DOI: 10.1016/j.arcmed.2018.01.004
Abstract: Hyperlipidemia is a systemic disease caused by abnormal human lipid metabolism. Dietary control and treatment on hyperlipidemia is now a popular therapy pathway. This paper focuses on the medicine food homology (MFH) species used in… read more here.
Keywords: medicine; food homology; hyperlipidemia; used china ... See more keywords