Paeonol inhibits NLRP3 mediated inflammation in rat endothelial cells by elevating hyperlipidemic rats plasma exosomal miRNA-223.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2020.173473
Abstract: Atherosclerosis (AS) is a multifactorial chronic inflammatory disease, and hyperlipidemia is the important factors leading to AS, which can cause vascular endothelial dysfunction. Paeonol (Pae) is a potential therapeutic drug for AS, and we have… read more here.
Keywords: elevating hyperlipidemic; rats plasma; mediated inflammation; hyperlipidemic rats ... See more keywords
Effects of Tea Seed Oil on Hyperlipidemic Rats Induced by High-fat Diet
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DOI: 10.3136/fstr.23.101
Abstract: To explore the hypolipidemic and hepatoprotective effects of tea seed oil, we administered tea seed oil and olive oil to rats to construct the rat hyperlipidemic model induced by high-fat diet, determined biochemical parameters in… read more here.
Keywords: seed; tea seed; hyperlipidemic rats; induced high ... See more keywords
Molecular characterization of gut microbiota in high‑lipid diet‑induced hyperlipidemic rats treated with simvastatin.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2020.4516
Abstract: Hyperlipidemia is a major risk factor for cardiovascular diseases. Simvastatin (SV), a cholesterol‑lowering agent, has been widely used in the treatment of hyperlipidemia. Gut microbiota is known to influence drug response, including that to statins.… read more here.
Keywords: hyperlipidemic rats; molecular characterization; microbiota; characterization gut ... See more keywords
Berberine Ameliorates Brain Inflammation in Poloxamer 407-Induced Hyperlipidemic Rats
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DOI: 10.5213/inj.1938216.108
Abstract: Purpose Hyperlipidemia, which promotes the development of atherosclerosis, ischemic stroke, and other forms of brain injury, can be induced by poloxamer-407. Berberine is a primary pharmacological active component of Coptidis Rhizoma that has a number… read more here.
Keywords: rats berberine; hyperlipidemic rats; inflammation; 407 induced ... See more keywords