Neuroprotective role of taurine on MK-801-induced memory impairment and hyperlocomotion in zebrafish
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2020.104710
Abstract: Schizophrenia is a neuropsychiatric condition that reaches around 1% of people worldwide. Because taurine exerts a neuroprotective role in the brain, this molecule is a promising candidate to reduce schizophrenia-like symptoms. Here, we investigated a… read more here.
Keywords: 801 induced; induced memory; hyperlocomotion; role ... See more keywords
Co-administration of cannabidiol and ketamine induces antidepressant-like effects devoid of hyperlocomotor side-effects
Sign Up to like & getrecommendations! Published in 2021 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2021.108679
Abstract: BACKGROUND AND PURPOSE Although useful as a rapid-acting antidepressant drug, ketamine is known to induce psychotomimetic effects, which may interfere with its therapeutic use. Cannabidiol (CBD) is a non-psychostimulant compound from Cannabis sativa, which has… read more here.
Keywords: cbd; ketamine; effect; antidepressant effect ... See more keywords
CB1 Receptor Silencing Attenuates Ketamine-Induced Hyperlocomotion Without Compromising Its Antidepressant-Like Effects.
Sign Up to like & getrecommendations! Published in 2022 at "Cannabis and cannabinoid research"
DOI: 10.1089/can.2022.0072
Abstract: Introduction: The antidepressant properties of ketamine have been extensively demonstrated in experimental and clinical settings. However, the psychotomimetic side effects still limit its wider use as an antidepressant. It was recently observed that endocannabinoids are… read more here.
Keywords: antidepressant like; antidepressant; hyperlocomotion; cb1r ... See more keywords
Neurobehavioral Differences of Valproate and Risperidone on MK-801 Inducing Acute Hyperlocomotion in Mice
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DOI: 10.1155/2022/1048463
Abstract: Objective The glutamate system plays a major role in the development of neuropsychiatric disorders such as addiction, epilepsy, dementia, and psychosis. MK-801 (dizocilpine), an uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, could increase locomotor activity and stereotyped… read more here.
Keywords: hyperlocomotion; risperidone valproic; risperidone; valproic acid ... See more keywords