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Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.am2020-5705
Abstract: High tumor mutational burden (hypermutation) is observed in some gliomas; however, its mechanisms of development and whether it predicts immunotherapy response are poorly understood. Here, we comprehensively analyze the molecular determinants of mutational burden and…
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Keywords:
gliomas;
implications hypermutation;
mechanisms therapeutic;
therapeutic implications ... See more keywords