Connexin 43 contributes to temporomandibular joint inflammation induced-hypernociception via sodium channel 1.7 in trigeminal ganglion
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DOI: 10.1016/j.neulet.2019.134301
Abstract: We previously demonstrated that sodium channel 1.7 (Nav1.7) in trigeminal ganglion (TG) was a critical factor in temporomandibular joint (TMJ) inflammation-induced hypernociception, but the mechanism underlying inflammation-induced upregulation of Nav1.7 remained unclear. Glial-neuron interaction plays… read more here.
Keywords: induced hypernociception; hypernociception; sodium channel; inflammation ... See more keywords
The P2X7 Receptor, Cathepsin S and Fractalkine in the Trigeminal Subnucleus Caudalis Signal Persistent Hypernociception in Temporomandibular Rat Joints
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DOI: 10.1016/j.neuroscience.2018.09.005
Abstract: Temporomandibular joint (TMJ) is frequently involved with rheumatoid arthritis with a high prevalence that could result in a chronic pain state. Once the disease is established in the joint, the antigen-specific immune reaction initiates a… read more here.
Keywords: induced arthritis; hypernociception; cathepsin fractalkine; trigeminal subnucleus ... See more keywords
Botulinum toxin type A reduces inflammatory hypernociception induced by arthritis in the temporomadibular joint of rats
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DOI: 10.1016/j.toxicon.2017.02.010
Abstract: Objective This study aimed to investigate the antinociceptive effects of Botulinum toxin type A (BoNT‐A) on persistent inflammatory hypernociception induced by arthritis in the temporomandibular joint (TMJ) of rats. Material and methods Wistar rats were… read more here.
Keywords: hypernociception; inflammatory hypernociception; toxin type; botulinum toxin ... See more keywords