Articles with "hyperosmolarity induced" as a keyword



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Copolymer Micelle-administered Melatonin Ameliorates Hyperosmolarity-induced Ocular Surface Damage through Regulating PINK1-mediated Mitophagy

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Published in 2022 at "Current Eye Research"

DOI: 10.1080/02713683.2021.2022163

Abstract: Abstract Purpose To investigate the role and mechanism of melatonin-loaded polymer polyvinyl caprolactam–polyvinyl acetate–polyethyleneglycol graft copolymer micelles (Mel-Mic) in dry eye disease (DED). Methods In vitro, the apoptosis and reactive oxygen species (ROS) generation in… read more here.

Keywords: induced ocular; ameliorates hyperosmolarity; hyperosmolarity induced; hyperosmolarity ... See more keywords
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Edaravone protects against hyperosmolarity-induced oxidative stress and apoptosis in primary human corneal epithelial cells

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Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0174437

Abstract: An increase in the osmolarity of tears induced by excessive evaporation of the aqueous tear phase is a major pathological mechanism behind dry eye. Exposure of epithelial cells on the surface of the human eye… read more here.

Keywords: epithelial cells; apoptosis; hyperosmolarity induced; hyperosmolarity ... See more keywords