Analysis of Comorbidities, Clinical Outcomes, and Parathyroidectomy in Adults With Primary Hyperparathyroidism
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.15396
Abstract: This cohort study examines the association of fractures, cardiovascular events, and mortality with untreated primary hyperparathyroidism and with surgical treatment. read more here.
Keywords: clinical outcomes; comorbidities clinical; outcomes parathyroidectomy; primary hyperparathyroidism ... See more keywords
Hyperparathyroidism in Patients With X‐Linked Hypophosphatemia
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DOI: 10.1002/jbmr.3992
Abstract: X‐linked hypophosphatemia (XLH) is characterized by increased activity of circulating FGF23 resulting in renal phosphate wasting and abnormal bone mineralization. Hyperparathyroidism may develop in XLH patients; however, its prevalence, pathogenesis, and clinical presentation are not… read more here.
Keywords: pth; hypercalcemic hyperparathyroidism; pth concentrations; hyperparathyroidism ... See more keywords
Effects of Parathyroidectomy on Quality of Life: 10 Years of Data From a Prospective Randomized Controlled Trial on Primary Hyperparathyroidism (the SIPH‐Study)
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4199
Abstract: Primary hyperparathyroidism (PHPT) was previously considered a disease presenting with multiorgan involvement and a wide range of symptoms. Today, the disease presents with no symptoms or mild symptomatology in most patients. Data regarding nonspecific symptoms… read more here.
Keywords: randomized controlled; prospective randomized; hyperparathyroidism; primary hyperparathyroidism ... See more keywords
Primary Hyperparathyroidism is Underdiagnosed and Suboptimally Treated in the Clinical Setting
Sign Up to like & getrecommendations! Published in 2018 at "World Journal of Surgery"
DOI: 10.1007/s00268-018-4574-1
Abstract: PurposeTo evaluate whether patients presenting with laboratory results consistent with primary hyperparathyroidism (pHPT) are managed in accordance with guidelines.MethodsThe laboratory database at a hospital in Sweden, serving 127,000 inhabitants, was searched for patients with biochemically… read more here.
Keywords: clinical setting; primary hyperparathyroidism; hyperparathyroidism; suboptimally treated ... See more keywords
Normocalcaemic primary hyperparathyroidism: a diagnostic and therapeutic algorithm
Sign Up to like & getrecommendations! Published in 2017 at "Langenbeck's Archives of Surgery"
DOI: 10.1007/s00423-017-1617-2
Abstract: In recent years, there has been increasing interest in understanding the implications of diagnosing normocalcaemic primary hyperparathyroidism (nPHPT). Many patients hope that nPHPT might explain some of their symptoms, but surgeons hesitate to offer treatment… read more here.
Keywords: therapeutic algorithm; hyperparathyroidism; primary hyperparathyroidism; diagnostic therapeutic ... See more keywords
Body mass index is associated with hyperparathyroidism in pediatric kidney transplant recipients
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Nephrology"
DOI: 10.1007/s00467-020-04796-w
Abstract: Background Hyperparathyroidism persists in up to 50% of pediatric kidney transplant recipients. The aims of this study were to describe the evolution of parathyroid hormone (PTH) in the first year after transplantation and to identify… read more here.
Keywords: hyperparathyroidism; transplant; associated hyperparathyroidism; transplantation ... See more keywords
Postsurgical Evaluation of Secondary Nephrogenic Hyperparathyroidism
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DOI: 10.1007/s11596-019-2028-0
Abstract: SummaryParathyroidectomy is useful for the treatment of secondary hyperparathyroidism (SHPT) caused by chronic renal failure. The following three types of parathyroidectomy can be performed: subtotal parathyroidectomy, total parathyroidectomy and total parathyroidectomy plus autologous transplantation (tPTX+AT).… read more here.
Keywords: hyperparathyroidism; evaluation secondary; nephrogenic hyperparathyroidism; serum ... See more keywords
Osteitis fibrosa cystica—a forgotten radiological feature of primary hyperparathyroidism
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DOI: 10.1007/s12020-017-1414-2
Abstract: SummaryAlthough bone disease and stone disease are the universally accepted classical manifestations of primary hyperparathyroidism, clinical parathyroid bone disease is rarely seen today in the United States ( read more here.
Keywords: hyperparathyroidism; disease; osteitis fibrosa; primary hyperparathyroidism ... See more keywords
A novel long-range deletion spanning CDC73 and upper-stream genes discovered in a kindred of familial primary hyperparathyroidism
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DOI: 10.1007/s12020-021-02917-5
Abstract: To confirm the exact break-point of a novel long-range deletion discovered in one female parathyroid carcinoma (PC) patient who has a strong family history suggesting familial hyperparathyroidism, and to investigate the expression of parafibromin in… read more here.
Keywords: deletion spanning; hyperparathyroidism; range deletion; deletion ... See more keywords
Management of Post-transplant Hyperparathyroidism and Bone Disease
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DOI: 10.1007/s40265-019-01074-4
Abstract: Significant advances in immunosuppressive therapies have been made in renal transplantation, leading to increased allograft and patient survival. Despite improvement in overall patient survival, patients continue to require management of persistent post-transplant hyperparathyroidism. Medications that… read more here.
Keywords: hyperparathyroidism; disease; management; post transplant ... See more keywords
Whole exome sequencing in familial isolated primary hyperparathyroidism
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-019-01107-5
Abstract: Purpose Familial isolated hyperparathyroidism (FIHP) is a rare inherited disease accounting for 1% of all cases of primary hyperparathyroidism (PHPT). It is genetically heterogeneous being associated with mutations in different genes, including MEN1 , CDC73… read more here.
Keywords: exome sequencing; primary hyperparathyroidism; hyperparathyroidism; disease ... See more keywords