The potential of oxytocin for the treatment of hyperphagia in Prader-Willi Syndrome
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Orphan Drugs"
DOI: 10.1080/21678707.2018.1451326
Abstract: Prader-Willi syndrome (PWS) is a complex, multisystem neurodevelopmental disorder that occurs with a frequency of approximately 1/10,000 to 1/30,000 . PWS results from the loss of expression of paternally derived genes by a variety of… read more here.
Keywords: individuals pws; hyperphagia; willi syndrome; prader willi ... See more keywords
Hyperphagia in Alzheimer's disease, its transient nature, and potentially reversible causes
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DOI: 10.1111/psyg.12432
Abstract: Hyperphagia is characterized by increased food intake, active searching for food in between meals, and loss of satiety. It has been observed in patients with impaired cognitive function. In this case series, we describe four… read more here.
Keywords: hyperphagia; alzheimer disease; case; megestrol ... See more keywords
Psychometric evaluation of novel hyperphagia questionnaires in a real-world setting for patients with a rare MC4R pathway disease
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DOI: 10.1186/s13023-025-03948-1
Abstract: There are no validated measures to assess hyperphagia associated with rare MC4R pathway diseases, such as Bardet-Biedl Syndrome (BBS). Symptoms of Hyperphagia© (SoH) and Impacts of Hyperphagia© (IoH) are novel questionnaires designed to assess signs… read more here.
Keywords: caregiver observer; hyperphagia; mc4r pathway; soh caregiver ... See more keywords
AZP-531, an unacylated ghrelin analog, improves food-related behavior in patients with Prader-Willi syndrome: A randomized placebo-controlled trial
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DOI: 10.1371/journal.pone.0190849
Abstract: Context and objective Prader-Willi syndrome (PWS) is characterized by early-onset hyperphagia and increased circulating levels of the orexigenic Acylated Ghrelin (AG) hormone with a relative deficit of Unacylated Ghrelin (UAG). AZP-531, a first-in-class UAG analog,… read more here.
Keywords: hyperphagia; prader willi; placebo; azp 531 ... See more keywords
The Hyperphagia Questionnaire: Insights From a Multicentric Validation Study in Individuals With Prader Willi Syndrome
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.829486
Abstract: Background/Objectives The present study aimed to validate the Italian version of the Hyperphagia Questionnaire (HQ), a 11-items questionnaire developed to assess hyperphagia in individuals with Prader-Willi syndrome (PWS). This is a complex neurodevelopmental disorder characterized… read more here.
Keywords: individuals prader; hyperphagia; prader willi; age ... See more keywords