Screening of tau protein kinase inhibitors in a tauopathy-relevant cell-based model of tau hyperphosphorylation and oligomerization
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DOI: 10.1371/journal.pone.0224952
Abstract: Tauopathies are a class of neurodegenerative disorders characterized by abnormal deposition of post-translationally modified tau protein in the human brain. Tauopathies are associated with Alzheimer’s disease (AD), chronic traumatic encephalopathy (CTE), and other diseases. Hyperphosphorylation… read more here.
Keywords: hyperphosphorylation oligomerization; inhibitor; kinase; hyperphosphorylation ... See more keywords