Hyperspectral imaging to accurately segment skin erythema and hyperpigmentation in cutaneous chronic graft-versus-host disease.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biophotonics"
DOI: 10.1002/jbio.202300009
Abstract: In 15 patients with the inflammatory skin condition chronic graft-versus-host-disease, hyperspectral imaging accurately delineated active erythema and post-inflammatory hyperpigmentation. The method was validated by dermatologist-approved confident delineations of only definitely affected and definitely unaffected areas… read more here.
Keywords: chronic graft; disease; hyperspectral imaging; hyperpigmentation ... See more keywords
The regulation of protein kinase casein kinase II by apigenin is involved in the inhibition of ultraviolet B‐induced macrophage migration inhibitory factor‐mediated hyperpigmentation
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6597
Abstract: Ultraviolet (UV) radiation elicits melanogenesis and pigmentation in the skin. Apigenin (4′,5,7‐trihydroxyflavone [AGN]) is a plant flavone contained in various herbs, fruits, and vegetables. We herein investigated antimelanogenic properties of AGN and the molecular mechanisms… read more here.
Keywords: macrophage migration; inhibitory factor; hyperpigmentation; migration inhibitory ... See more keywords
Effects of laser therapy on periorbital hyperpigmentation: a systematic review on current studies
Sign Up to like & getrecommendations! Published in 2021 at "Lasers in Medical Science"
DOI: 10.1007/s10103-020-03241-6
Abstract: Periorbital hyperpigmentation is a problem with complex multifactorial etiology, with early knowledge expanding. The purpose of the present study was to review studies on the efficacy of laser on periorbital hyperpigmentation. A systematic review of… read more here.
Keywords: systematic review; hyperpigmentation systematic; hyperpigmentation; periorbital hyperpigmentation ... See more keywords
Mucocutaneous hyperpigmentation.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of internal medicine"
DOI: 10.1016/j.ejim.2017.12.015
Abstract: A 43-year-old woman with a 1-year history of 6-kg weight loss and weakness was diagnosed with primary hypothyroidism and started levothyroxine one week before. She presented to the emergency department with a 4-day history of… read more here.
Keywords: medicine; mucocutaneous hyperpigmentation; hyperpigmentation;
A case of hyperpigmentation induced by hydroxychloroquine and quinacrine in a patient with systemic lupus erythematosus and review of the literature
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Women's Dermatology"
DOI: 10.1016/j.ijwd.2020.06.009
Abstract: Hydroxychloroquine (HQ) and quinacrine are widely used antimalarials for systemic lupus erythematosus (SLE) and other autoimmune diseases. We report a case of antimalarial-induced hyperpigmentation in a 57-year old African-American woman. The patient had a long-standing… read more here.
Keywords: hydroxychloroquine quinacrine; systemic lupus; lupus erythematosus; hyperpigmentation ... See more keywords
Postinflammatory hyperpigmentation: A comprehensive overview: Epidemiology, pathogenesis, clinical presentation, and noninvasive assessment technique.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2017.01.035
Abstract: Postinflammatory hyperpigmentation (PIH) commonly occurs after various endogenous and exogenous stimuli, especially in dark-skinned individuals. PIH is one of the most common complications of procedures performed using laser and other light sources. The severity of PIH is… read more here.
Keywords: epidemiology pathogenesis; hyperpigmentation; epidemiology; clinical presentation ... See more keywords
Novel formulations for topical delivery of tranexamic acid: Assessing the need of epidermal targeting for hyperpigmentation disorders.
Sign Up to like & getrecommendations! Published in 2023 at "Expert opinion on drug delivery"
DOI: 10.1080/17425247.2023.2206645
Abstract: INTRODUCTION Tranexamic acid is used for the treatment of hyperpigmentation and the topical route is the most favorable route for its administration. Tranexamic acid lowers plasmin and tyrosinase, which reduces melanin and skin hyperpigmentation. Low… read more here.
Keywords: topical delivery; epidermal targeting; hyperpigmentation; delivery ... See more keywords
A Rare Case of Protein-Losing Enteropathy, Alopecia, Hyperpigmentation and Dystrophy of the Nails: A Case Report
Sign Up to like & getrecommendations! Published in 2022 at "Inflammatory Bowel Diseases"
DOI: 10.1093/ibd/izac154
Abstract: A 69-year-old man with Indian parents living in the Netherlands since 1975 was referred to our tertiary center with progressive complaints of upper abdominal pain, progressive diarrhea, and 11 kg of weight gain in 2… read more here.
Keywords: dystrophy nails; rare case; case protein; case ... See more keywords
Particulate matter 2.5 induced hyperpigmentation in reconstructed human epidermis model (MelaKutis®)
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000001934
Abstract: To the Editor: Epidemiological studies have confirmed Biocell Biotechnology), and NHEMs in Medium 254 that fine particulate matter (PM2.5) is related to skin hyperpigmentation, but experimental evidence is lacking. Here, we used normal human epidermal… read more here.
Keywords: reconstructed human; particulate matter; human epidermis; hyperpigmentation ... See more keywords
Rare ashy dermatosis‐like hyperpigmentation associated with osimertinib
Sign Up to like & getrecommendations! Published in 2022 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.14383
Abstract: Osimertinib, a third‐generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), is the most reliable EGFR‐TKI and is widely used as the first‐line treatment for EGFR mutation‐positive non‐small cell lung cancer. Pigmentary changes caused… read more here.
Keywords: dermatosis like; ashy dermatosis; like hyperpigmentation; rare ashy ... See more keywords
Cutaneous hyperpigmentation and familial gastrointestinal stromal tumour associated with KIT mutation
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Experimental Dermatology"
DOI: 10.1111/ced.13757
Abstract: Gastrointestinal stromal tumours (GISTs) are mesenchymal tumours arising in the gastrointestinal tract. Early detection, before metastasis occurs, is important as complete surgical excision achieves cure. Approximately 85% of GISTs are associated with mutations in the… read more here.
Keywords: cutaneous hyperpigmentation; hyperpigmentation; gastrointestinal stromal; gist ... See more keywords