Cardiomyocyte hyperplasia and immaturity but not hypertrophy are characteristic features of patients with RASopathies.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of molecular and cellular cardiology"
DOI: 10.2139/ssrn.4192490
Abstract: AIMS RASopathies are caused by mutations in genes that alter the MAP kinase pathway and are marked by several malformations with cardiovascular disorders as the predominant cause of mortality. Mechanistic insights in the underlying pathogenesis… read more here.
Keywords: features patients; hyperplasia immaturity; characteristic features; cardiomyocyte hyperplasia ... See more keywords