Diffusion weighted hyperpolarized 129Xe MRI of the lung with 2D and 3D (FLORET) spiral
Sign Up to like & getrecommendations! Published in 2022 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.29518
Abstract: To enable efficient hyperpolarized 129Xe diffusion imaging using 2D and 3D (Fermat Looped, ORthogonally Encoded Trajectories, FLORET) spiral sequences and demonstrate that 129Xe ADCs obtained using these sequences are comparable to those obtained using a… read more here.
Keywords: weighted hyperpolarized; 129xe mri; floret spiral; diffusion weighted ... See more keywords
Imaging gas‐exchange lung function and brain tissue uptake of hyperpolarized 129Xe using sampling density‐weighted MRSI
Sign Up to like & getrecommendations! Published in 2023 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.29602
Abstract: Imaging of the different resonances of hyperpolarized 129Xe in the brain and lungs was performed using a 3D sampling density‐weighted MRSI technique in healthy volunteers. read more here.
Keywords: brain; using sampling; weighted mrsi; sampling density ... See more keywords
Application of a 2D frequency encoding sectoral approach to hyperpolarized 129Xe MRI at low field.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of magnetic resonance"
DOI: 10.1016/j.jmr.2022.107159
Abstract: Inhaled hyperpolarized 129Xe MRI is a non-invasive and radiation risk free lung imaging method, which can directly measure the business unit of the lung where gas exchange occurs: the alveoli and acinar ducts (lung function).… read more here.
Keywords: hyperpolarized 129xe; 129xe mri; frequency; encoding sectoral ... See more keywords
Quantification of Ventilation and Gas Uptake in Free-Breathing Mice With Hyperpolarized 129Xe MRI
Sign Up to like & getrecommendations! Published in 2019 at "IEEE Transactions on Medical Imaging"
DOI: 10.1109/tmi.2019.2911293
Abstract: Hyperpolarized 129Xe magnetic resonance imaging is a powerful modality capable of assessing lung structure and function. While it has shown promise as a clinical tool for the longitudinal assessment of lung function, its utility as… read more here.
Keywords: gas; ventilation; hyperpolarized 129xe; phase images ... See more keywords
Imaging Human Brain Perfusion with Inhaled Hyperpolarized 129Xe MR Imaging.
Sign Up to like & getrecommendations! Published in 2018 at "Radiology"
DOI: 10.1148/radiol.2017162881
Abstract: Purpose To evaluate the feasibility of directly imaging perfusion of human brain tissue by using magnetic resonance (MR) imaging with inhaled hyperpolarized xenon 129 (129Xe). Materials and Methods In vivo imaging with 129Xe was performed… read more here.
Keywords: inhaled hyperpolarized; perfusion; human brain; hyperpolarized 129xe ... See more keywords
Human upper-airway respiratory airflow: In vivo comparison of computational fluid dynamics simulations and hyperpolarized 129Xe phase contrast MRI velocimetry
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0256460
Abstract: Computational fluid dynamics (CFD) simulations of respiratory airflow have the potential to change the clinical assessment of regional airway function in health and disease, in pulmonary medicine and otolaryngology. For example, in diseases where multiple… read more here.
Keywords: respiratory airflow; hyperpolarized 129xe; mri; cfd ... See more keywords
Preclinical MRI Using Hyperpolarized 129Xe
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27238338
Abstract: Although critical for development of novel therapies, understanding altered lung function in disease models is challenging because the transport and diffusion of gases over short distances, on which proper function relies, is not readily visualized.… read more here.
Keywords: gas; spectroscopy; using hyperpolarized; mri using ... See more keywords
Towards Probing Conformational States of Y2 Receptor Using Hyperpolarized 129Xe NMR
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28031424
Abstract: G protein-coupled receptors can adopt many different conformational states, each of them exhibiting different restraints towards downstream signaling pathways. One promising strategy to identify and quantify this conformational landscape is to introduce a cysteine at… read more here.
Keywords: probing conformational; conformational states; towards probing; states receptor ... See more keywords
Production of Hyperpolarized 129Xe Using Spin Exchange Optical Pumping
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Korean Physical Society"
DOI: 10.3938/jkps.73.1458
Abstract: We present a constructed setup for polarizing 129Xe noble gas. Hyperpolarized 129Xe has been obtained via spin exchange with an optically pumped rubidium vapor. Optical pumping is based on polarizing the valence electron of rubidium… read more here.
Keywords: spin exchange; 129xe using; optical pumping; hyperpolarized 129xe ... See more keywords