Articles with "hypersensitivity responses" as a keyword



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Protein re-surfacing of E. coli L-Asparaginase to evade pre-existing anti-drug antibodies and hypersensitivity responses

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1016179

Abstract: The optimal use of many biotherapeutics is restricted by Anti-drug antibodies (ADAs) and hypersensitivity responses which can affect potency and ability to administer a treatment. Here we demonstrate that Re-surfacing can be utilized as a… read more here.

Keywords: hypersensitivity responses; pre existing; drug antibodies; anti drug ... See more keywords