Therapeutic potential of carbon monoxide in hypertension-induced vascular smooth muscle cell damage revisited: from physiology and pharmacology.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2022.115008
Abstract: As a chronic and progressive disorder, hypertension remains to be a serious public health problem around the world. Among the different types of hypertension, pulmonary arterial hypertension (PAH) is a devastating disease associated with pulmonary… read more here.
Keywords: hypertension induced; carbon monoxide; physiology; vascular remodeling ... See more keywords
Mangiferin alleviates hypertension induced by hyperuricemia via increasing nitric oxide releases.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmacological sciences"
DOI: 10.1016/j.jphs.2018.05.008
Abstract: Mangiferin, a natural glucosyl xanthone, was confirmed to be an effective uric acid (UA)- lowering agent with dual action of inhibiting production and promoting excretion of UA. In this study, we aimed to evaluate the… read more here.
Keywords: nitric oxide; hyperuricemia via; induced hyperuricemia; hypertension induced ... See more keywords
Resveratrol and regular exercise may attenuate hypertension-induced cardiac dysfunction through modulation of cellular stress responses.
Sign Up to like & getrecommendations! Published in 2022 at "Life sciences"
DOI: 10.1016/j.lfs.2022.120424
Abstract: AIMS Hypertension is one of the major causes of cardiac damage. In this study, the effects of resveratrol supplementation and regular exercise on hypertension-induced cellular stress responses of myocardium were compared. MAIN METHODS Hypertension was… read more here.
Keywords: hypertension induced; stress; exercise; resveratrol regular ... See more keywords
Prevention of hypertension-induced vascular dementia by Lactobacillus paracasei subsp. paracasei NTU 101-fermented products
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DOI: 10.1080/13880209.2016.1253109
Abstract: Abstract Context: Numerous etiological studies have established positive clinical association between hypertension and vascular dementia (VaD). Lactobacillus paracasei subsp. paracasei NTU 101-fermented products have been shown to decrease vascular risk factors such as hypertension, atherosclerosis,… read more here.
Keywords: lactobacillus paracasei; paracasei subsp; hypertension induced; hypertension ... See more keywords
Lovastatin attenuates hypertension induced by renal tubule‐specific knockout of ATP‐binding cassette transporter A1, by inhibiting epithelial sodium channels
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Pharmacology"
DOI: 10.1111/bph.14775
Abstract: We have shown that cholesterol is synthesized in the principal cells of renal cortical collecting ducts (CCD) and stimulates the epithelial sodium channels (ENaC). Here we have determined whether lovastatin, a cholesterol synthesis inhibitor, can… read more here.
Keywords: hypertension induced; atp binding; binding cassette; epithelial sodium ... See more keywords
Metabolic rewiring of the hypertensive kidney
Sign Up to like & getrecommendations! Published in 2019 at "Science Signaling"
DOI: 10.1126/scisignal.aax9760
Abstract: Multi-omics analyses reveal that metabolic changes occur early in hypertension-induced kidney disease. Metabolic changes under pressure Chronic hypertension causes irreversible damage to the kidneys. Rinschen et al. performed multi-omics analyses of kidney tissue from rats… read more here.
Keywords: metabolic changes; hypertension induced; disease; hypertension ... See more keywords
Effects of Finerenone Combined with Empagliflozin in a Model of Hypertension-Induced End-Organ Damage
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DOI: 10.1159/000516213
Abstract: Introduction: The nonsteroidal mineralocorticoid receptor (MR) antagonist finerenone and sodium-glucose cotransporter-2 (SGLT2) inhibitors have demonstrated clinical benefits in CKD patients with type 2 diabetes. Clinical data analyzing the potential value of a combination therapy are… read more here.
Keywords: combination; low dose; dose combination; hypertension induced ... See more keywords
Abstract P141: Toll Like Receptor 4 Mediated Autophagy Contributes to Hypertension-Induced Kidney Injury
Sign Up to like & getrecommendations! Published in 2019 at "Hypertension"
DOI: 10.1161/hyp.74.suppl_1.p141
Abstract: Hypertension is the second leading cause of chronic kidney disease in the world. Angiotensin II (Ang II) induced Toll-like receptor 4, TLR4, activation contributes to hypertension-induced renal inflammation and fibrosis. Recently, we showed that mice… read more here.
Keywords: toll like; hypertension induced; like receptor; hypertension ... See more keywords
Pattern of sympathetic vasomotor activity in a model of hypertension induced by nitric oxide synthase blockade
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DOI: 10.14814/phy2.14183
Abstract: We aimed to investigate the effects of nitric oxide (NO) synthesis inhibition by NO synthase inhibitor N‐nitro‐L‐arginine‐methyl ester (L‐NAME) treatment on the sympathetic vasomotor nerve activity (SNA) on two sympathetic vasomotor nerves, the renal and… read more here.
Keywords: nitric oxide; sympathetic vasomotor; hypertension induced; synthase ... See more keywords
A Polyphenol-Rich Extract from Muscadine Grapes Prevents Hypertension-Induced Diastolic Dysfunction and Oxidative Stress
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DOI: 10.3390/antiox11102026
Abstract: Muscadine grapes are abundant in dietary polyphenols, but their effect on hypertension-induced cardiac damage is limited. This study assessed whether a muscadine grape skin/seed extract supplement (MGES) prevents hypertension-induced cardiac damage and oxidative stress. Male… read more here.
Keywords: hypertension; diastolic dysfunction; induced diastolic; oxidative stress ... See more keywords
FTIR Analysis of Renal Tissue for the Assessment of Hypertensive Organ Damage and proANP31–67 Treatment
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065196
Abstract: The kidneys are one of the main end organs targeted by hypertensive disease. Although the central role of the kidneys in the regulation of high blood pressure has been long recognized, the detailed mechanisms behind… read more here.
Keywords: damage; hypertension; hypertension induced; analysis ... See more keywords