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Published in 2017 at "World Journal of Pediatrics"
DOI: 10.1007/s12519-017-0056-z
Abstract: BackgroundSeveral studies have clearly demonstrated a significantly higher incidence of persistent pulmonary hypertension of the newborn (PPHN) in neonates delivered by caesarean section (CS) compared to those delivered vaginally. The pathophysiological factors underlying the link… read more here.
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Published in 2021 at "Clinics in perinatology"
DOI: 10.1016/j.clp.2021.05.009
Abstract: Persistent pulmonary hypertension of the newborn (PPHN) is a disorder of circulatory transition resulting in high pulmonary vascular resistance with extrapulmonary right-to-left shunts causing hypoxemia. There has been substantial gain in understanding of pathophysiology of… read more here.
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Published in 2022 at "Current problems in cardiology"
DOI: 10.1016/j.cpcardiol.2022.101181
Abstract: OBJECTIVE To examine echocardiographic (ECHO) parameters correlation with clinical severity indices, Alveolar- arterial gradient (A-a gradient), oxygenation index (OI) and clinical outcomes in newborns with persistent pulmonary hypertension of the newborn (PPHN). STUDY DESIGN Retrospective… read more here.
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Published in 2021 at "American journal of perinatology"
DOI: 10.1055/a-1711-0778
Abstract: Persistent pulmonary hypertension of the newborn, or PPHN, represents a challenging condition associated with high morbidity and mortality. Management is complicated by complex pathophysiology and limited neonatal specific evidence-based literature, leading to a lack of… read more here.
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Published in 2018 at "American Journal of Perinatology"
DOI: 10.1055/s-0037-1607213
Abstract: Abstract Objective This study aims to determine the risk factors and outcome of persistent pulmonary hypertension of the newborn (PPHN)‐associated acute kidney injury (AKI). Study Design Infants diagnosed with PPHN at Hat Yai Hospital from… read more here.
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Published in 2018 at "American Journal of Perinatology"
DOI: 10.1055/s-0038-1660462
Abstract: &NA; Persistent pulmonary hypertension of the newborn (PPHN) is a complication of several respiratory diseases characterized by an elevation in pulmonary vascular resistance with resultant right‐to‐left shunting of blood and severe hypoxemia in the neonatal… read more here.
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Published in 2019 at "Anesthesiology"
DOI: 10.1097/aln.0000000000002579
Abstract: Inhaled Nitric Oxide in Persistent Pulmonary Hypertension of the Newborn. By Roberts JD, Polaner DM, Lang P, and Zapol WM. Lancet 1992; 130:435-40. Reprinted with permission.NO has vasodilatory effects on the pulmonary vasculature in adults… read more here.
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Published in 2022 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001373
Abstract: Abstract: Persistent pulmonary hypertension of the newborn (PPHN) is characterized by pulmonary arterial remodeling mainly because of apoptosis resistance and excessive proliferation of pulmonary artery smooth muscle cells (PASMCs). Sildenafil is a phosphodiesterase-5 inhibitor. Some… read more here.
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Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000007303
Abstract: Rationale: Persistent pulmonary hypertension of the newborn (PPHN) is a syndrome of failed circulatory adaptation at birth with persisting increased pulmonary vascular resistance that is associated with high mortality rates especially in preterm infants. Patient… read more here.
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Published in 2017 at "Journal of Medical Case Reports"
DOI: 10.1186/s13256-017-1402-4
Abstract: BackgroundPersistent pulmonary hypertension is a well-known disease of the newborn that in most cases responds well to treatment with nitric oxide and treatment of any underlying causes. Genetic causes of persistent pulmonary hypertension of the… read more here.
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Published in 2021 at "Pakistan Journal of Medical Sciences"
DOI: 10.12669/pjms.37.5.2218
Abstract: Background & Objective: Persistent pulmonary hypertension of the newborn (PPHN) is described as severe respiratory failure along with hypoxaemia. PPHN is known to be linked with high morbidity and mortality around the world. This study… read more here.