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Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12119
Abstract: Abstract The INSPIRE trial was a Phase 3, open‐label, multicenter trial (LTI‐301) that enrolled patients with pulmonary arterial hypertension (PAH) ≥ 18 years of age who transitioned to Yutrepia from nebulized treprostinil (Transition) or added Yutrepia to…
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Keywords:
safety;
hypertension pah;
arterial hypertension;
trial ... See more keywords
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Published in 2019 at "Lung"
DOI: 10.1007/s00408-019-00283-8
Abstract: Epoprostenol, a synthetic prostaglandin I2 (PGI2) analog, has been the mainstay of treatment for severe pulmonary arterial hypertension (PAH) for the last two decades. Treprostinil, another synthetic prostaglandin analog, and selexipag, an oral selective Inositol…
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Keywords:
hypertension pah;
thyroid dysfunction;
prostacyclin;
dysfunction ... See more keywords
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Published in 2020 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(20)32728-5
Abstract: Many patients with PAH have comorbidities that may exclude them from clinical trials due to stringent inclusion criteria. The OPUS Registry ([NCT02126943][1]) is an ongoing, prospective, multicenter, US drug registry of patients newly treated with…
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Keywords:
comorbidities pulmonary;
arterial hypertension;
opus registry;
hypertension pah ... See more keywords