Genome-wide association studies categorized by class of anti-hypertensive drugs reveal complex pathogenesis of hypertension with drug resistance.
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DOI: 10.1002/cpt.2934
Abstract: Resistant hypertension is defined as uncontrolled blood pressure despite the use of three or more anti-hypertensive drugs of different classes. Though genetic factors may greatly contribute to hypertension with resistance to multiple drug classes, more… read more here.
Keywords: hypertensive drugs; hypertension; anti hypertensive; resistance ... See more keywords
The effects of anti-hypertensive drugs and the mechanism of hypertension in vascular smooth muscle cell-specific ATP2B1 knockout mice
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DOI: 10.1038/hr.2017.92
Abstract: ATP2B1 is a gene associated with hypertension. We reported previously that mice lacking ATP2B1 in vascular smooth muscle cells (VSMC ATP2B1 KO mice) exhibited high blood pressure and increased intracellular calcium concentration. The present study… read more here.
Keywords: anti hypertensive; blood pressure; hypertensive drugs; mice ... See more keywords
Coronavirus Disease 2019 and Hypertension: How Anti-Hypertensive Drugs Affect COVID-19 Medications and Vice Versa.
Sign Up to like & getrecommendations! Published in 2022 at "Current drug safety"
DOI: 10.2174/1574886317666220405121319
Abstract: BACKGROUND As a medical problem, hypertension is one of the most common disorders in cardiovascular disease. High blood pressure has been identified as one of the most familiar risk factors for the ongoing COVID-19 pandemic.… read more here.
Keywords: hypertensive drugs; coronavirus disease; hypertension; anti hypertensive ... See more keywords