Sulfatase 1 mediates the attenuation of Ang II‐induced hypertensive effects by CCL5 in vascular smooth muscle cells from spontaneously hypertensive rats
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DOI: 10.1016/j.cyto.2017.12.027
Abstract: &NA; Extracellular sulfatases, sulfatase 1 (Sulf1) and sulfatase 2 (Sulf2), play a pivotal role in cell signaling and carcinogenesis. Chemokine CCL5 inhibits Ang II‐induced hypertensive mediators via angiotensin II (Ang II) type 2 receptor (AT2… read more here.
Keywords: ang induced; ccl5; hypertensive effects; induced hypertensive ... See more keywords
Hypertensive effects of transforming growth factor-β1 in vascular smooth muscles cells from spontaneously hypertensive rats are mediated by sulfatase 2.
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DOI: 10.1016/j.cyto.2021.155754
Abstract: Extracellular sulfatases (sulfatase 1 and sulfatase 2) mediate up- or down-regulatory effects of cytokines on angiotensin II (Ang II)-induced expression of hypertensive mediators in hypertensive cells. The overproduction of transforming growth factor-β1 (TGF-β1) is associated… read more here.
Keywords: ang induced; hypertensive effects; tgf; shr vsmcs ... See more keywords
Anti-hypertensive effects of Callisia fragrans extract on Reno-vascular hypertensive rats
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DOI: 10.1080/10641963.2022.2065286
Abstract: ABSTRACT Objectives This study aims to investigate the anti-hypertensive effects of aqueous extract of Callisia fragrans and their underlying mechanism using a two-kidney one-clip (2K1C) model of reno-vascular hypertension in rats. Methods The reno-vascular hypertensive… read more here.
Keywords: fragrans extract; vascular hypertensive; anti hypertensive; hypertensive effects ... See more keywords