Altered microRNA regulation of short chain fatty acid receptors in the hypertensive kidney is normalized with hydrogen sulfide supplementation
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacological Research"
DOI: 10.1016/j.phrs.2018.06.012
Abstract: Graphical abstract Figure. No caption available. &NA; Hypertension affects nearly one third of the adult US population and is a significant risk factor for chronic kidney disease (CKD). An expanding body of recent studies indicates… read more here.
Keywords: supplementation; short chain; hypertensive kidney; chain fatty ... See more keywords
Evaluation of Biological Mechanisms of Eucommiae Folium in Hypertensive Kidney Injury by Integration of Untargeted Metabolomics and Network Pharmacology.
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DOI: 10.1021/acs.jproteome.0c00973
Abstract: Hypertensive kidney injury (Hki) is one of the most common complications of hypertension. Early prevention and treatment of renal injury in patients with hypertension is great significance. The study, which used an integrated ultraperformance liquid… read more here.
Keywords: network; eucommiae folium; pharmacology; network pharmacology ... See more keywords
Metabolic rewiring of the hypertensive kidney
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DOI: 10.1126/scisignal.aax9760
Abstract: Multi-omics analyses reveal that metabolic changes occur early in hypertension-induced kidney disease. Metabolic changes under pressure Chronic hypertension causes irreversible damage to the kidneys. Rinschen et al. performed multi-omics analyses of kidney tissue from rats… read more here.
Keywords: metabolic changes; hypertension induced; disease; hypertension ... See more keywords
Ang II (Angiotensin II)–Induced FGFR1 (Fibroblast Growth Factor Receptor 1) Activation in Tubular Epithelial Cells Promotes Hypertensive Kidney Fibrosis and Injury
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DOI: 10.1161/hypertensionaha.122.18657
Abstract: Background: Elevated Ang II (angiotensin II) level leads to a range of conditions, including hypertensive kidney disease. Recent evidences indicate that FGFR1 (fibroblast growth factor receptor 1) signaling may be involved in kidney injuries. In… read more here.
Keywords: angiotensin; kidney; ang; hypertensive kidney ... See more keywords