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Published in 2017 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000001170
Abstract: Hypertensive kidney disease classically entails nephroangiosclerosis and hyalinosis with glomerular damage. However, in recent years, several evidences showed that high blood pressure also injures tubular cells, inducing epithelial-to-mesenchymal transition and tubulointerstitial fibrosis. Recently investigated mechanisms…
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Keywords:
emerging pathogenetic;
hypertensive nephropathy;
moving classic;
nephropathy moving ... See more keywords
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Published in 2019 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13042
Abstract: Hypertensive nephropathy, clinically characterized by progressive renal fibrosis and inflammation, is a severe complication of hypertension. The objectives of this study were to investigate the roles of miR‐101a in relieving angiotensin II (Ang II)‐mediated hypertensive…
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Keywords:
hypertensive nephropathy;
mir 101a;
mouse model;
tgf smad3 ... See more keywords
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Published in 2022 at "Clinical Nursing Research"
DOI: 10.1177/10547738211073396
Abstract: The purpose of this study is to investigate the relationships among disease knowledge, self-efficacy, and quality of life in patients with hypertensive nephropathy. A cross-sectional and correlational design is employed in this study, and a…
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Keywords:
disease knowledge;
hypertensive nephropathy;
quality life;
self efficacy ... See more keywords
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Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.794768
Abstract: Importance Hypertension is a leading cause of end-stage renal disease (ESRD), but currently, those at risk are poorly identified. Objective To develop and validate a prediction model for the development of hypertensive nephropathy (HN). Design,…
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Keywords:
prediction model;
validation;
development;
prediction ... See more keywords
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Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1126972
Abstract: Background/aim: Hypertensive nephropathy (HN) is a common complication of hypertension. Traditional Chinese medicine has long been used in the clinical treatment of Hypertensive nephropathy. However, botanical drug prescriptions have not been summarized. The purpose of…
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Keywords:
botanical drugs;
shen formula;
gao shen;
retrospective cohort ... See more keywords
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Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22084230
Abstract: Hypertension induces renal fibrosis or tubular interstitial fibrosis, which eventually results in end-stage renal disease. Epithelial-to-mesenchymal transition (EMT) is one of the underlying mechanisms of renal fibrosis. Though previous studies showed that Ecklonia cava extracts…
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Keywords:
fibrosis;
spontaneously hypertensive;
hypertensive nephropathy;
hypertensive rats ... See more keywords