N‐methyl‐d‐aspartate receptor dysfunction in the prefrontal cortex of stroke‐prone spontaneously hypertensive rat/Ezo as a rat model of attention deficit/hyperactivity disorder
Sign Up to like & getrecommendations! Published in 2018 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12007
Abstract: We previously reported that stroke‐prone spontaneously hypertensive rat/Ezo (SHRSP/Ezo) has high validity as an attention deficit/hyperactivity disorder (AD/HD) animal model, based on its behavioral phenotypes, such as inattention, hyperactivity, and impulsivity. Fronto‐cortical dysfunction is implicated… read more here.
Keywords: stroke prone; spontaneously hypertensive; hyperactivity; hypertensive rat ... See more keywords
Protective effect of calcitriol on podocytes in spontaneously hypertensive rat
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Chinese Medical Association"
DOI: 10.1016/j.jcma.2018.01.010
Abstract: Background: Hypertension is a major global public health issue. Uncontrolled hypertension leads to organ damage, especially renal damage. Calcitriol is used to treat osteoporosis, promote bone formation, and increase bone mass. Previous studies have demonstrated… read more here.
Keywords: spontaneously hypertensive; compared group; group; group compared ... See more keywords
Retinal Vascular and Anatomical Features in the Spontaneously Hypertensive Rat
Sign Up to like & getrecommendations! Published in 2020 at "Current Eye Research"
DOI: 10.1080/02713683.2020.1752738
Abstract: ABSTRACT Purpose: To evaluate whether in vivo optical imaging methods and histology can detect comparable vascular and neuronal damage in the retina due to the effects of progressive chronic hypertension on the retinal vasculature and… read more here.
Keywords: spontaneously hypertensive; layer; hypertensive rat; shr ... See more keywords
Dynein Coordinates β2-Adrenoceptor-Mediated Relaxation in Normotensive and Hypertensive Rat Mesenteric Arteries
Sign Up to like & getrecommendations! Published in 2022 at "Hypertension"
DOI: 10.1161/hypertensionaha.122.19351
Abstract: Background: The voltage-gated potassium channel (Kv)7.4 and Kv7.5 channels contribute to the β-adrenoceptor-mediated vasodilatation. In arteries from hypertensive rodents, the Kv7.4 channel is downregulated and function attenuated, which contributes to the reduced β-adrenoceptor-mediated vasodilatation observed… read more here.
Keywords: adrenoceptor mediated; mediated vasodilatation; adrenoceptor; hypertensive rat ... See more keywords
The Assembled Genome of the Stroke-Prone Spontaneously Hypertensive Rat
Sign Up to like & getrecommendations! Published in 2022 at "Hypertension"
DOI: 10.1161/hypertensionaha.122.20140
Abstract: Background: We report the creation and evaluation of a de novo assembly of the genome of the spontaneously hypertensive rat, the most widely used model of human cardiovascular disease. Methods: The genome is assembled from… read more here.
Keywords: genome assembly; rat; reference; hypertensive rat ... See more keywords
Apolipoprotein E-depletion accelerates arterial fat deposition in the spontaneously hypertensive rat.
Sign Up to like & getrecommendations! Published in 2023 at "Experimental animals"
DOI: 10.1538/expanim.23-0012
Abstract: Hypertension and atherosclerosis are often found in one patient causing serious cardiovascular events. An animal model simultaneously expressing hypertension and atherosclerosis would be useful to study such a complex risk status. We therefore attempted to… read more here.
Keywords: hypertension; fat deposition; atherosclerosis; hypertensive rat ... See more keywords