Boosting the effects of hyperthermia-based anticancer treatments by HSP90 inhibition
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DOI: 10.18632/oncotarget.22142
Abstract: Hyperthermia – application of supra-physiological temperatures to cells, tissues or organs – is a pleiotropic treatment that affects most aspects of cellular metabolism, but its effects on DNA are of special interest in the context… read more here.
Keywords: hyperthermia; treatment; hyperthermia based; hsp90 inhibition ... See more keywords
Evaluation of the Heat Shock Protein 90 Inhibitor Ganetespib as a Sensitizer to Hyperthermia-Based Cancer Treatments
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DOI: 10.3390/cancers14215250
Abstract: Simple Summary Hyperthermia boosts the effects of radio- and chemotherapy regimens, but its clinical potential is hindered by the ability of (cancer) cells to activate a protective mechanism known as the heat stress response. Strategies… read more here.
Keywords: hyperthermia; inhibitor ganetespib; efficacy; heat ... See more keywords