Comparison of Intracranial Pressure Measurements Before and After Hypertonic Saline or Mannitol Treatment in Children With Severe Traumatic Brain Injury
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.0891
Abstract: Key Points Question How commonly are hyperosmolar therapies used in the management of severe traumatic brain injury in children, and which agent—mannitol or hypertonic saline solution—is associated with greater decreases in intracranial pressure (ICP) and/or… read more here.
Keywords: traumatic brain; mannitol; brain injury; hypertonic saline ... See more keywords
Effect of Nebulized Hypertonic Saline Treatment in Emergency Departments on the Hospitalization Rate for Acute Bronchiolitis: A Randomized Clinical Trial
Sign Up to like & getrecommendations! Published in 2017 at "JAMA Pediatrics"
DOI: 10.1001/jamapediatrics.2017.1333
Abstract: Importance Acute bronchiolitis is the leading cause of hospitalization among infants. Previous studies, underpowered to examine hospital admission, have found a limited benefit of nebulized hypertonic saline (HS) treatment in the pediatric emergency department (ED).… read more here.
Keywords: bronchiolitis; acute bronchiolitis; treatment; group ... See more keywords
Could This Be the Last Word on Hypertonic Saline?
Sign Up to like & getrecommendations! Published in 2017 at "JAMA pediatrics"
DOI: 10.1001/jamapediatrics.2017.1345
Abstract: Only a few years ago, hypertonic saline had a reputation as a potentially evidence-based therapy for acute viral bronchiolitis in young children.1 However, as more trials were published, the evidence seemed to devolve. One assessment… read more here.
Keywords: bronchiolitis; risk; hospitalization; hypertonic saline ... See more keywords
Does nebulized hypertonic saline shorten hospitalization in young children with acute viral wheezing?
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.23924
Abstract: Although previous studies have shown benefits of nebulized hypertonic saline (HS) for improving airway clearance and shortening hospitalization in infants with bronchiolitis, prospective blinded studies in preschool children with acute viral wheezing are limited. read more here.
Keywords: viral wheezing; acute viral; nebulized hypertonic; hypertonic saline ... See more keywords
Ethanol-Induced Taurine Elevation in the Rat Dorsal Striatum.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-94-024-1079-2_15
Abstract: In the search for the primary mechanism underlying the dopamine elevating properties of ethanol we have established that raised levels of taurine in the nucleus accumbens (nAc) is pivotal. In the nAc, the release of… read more here.
Keywords: hypertonic saline; striatum; taurine dopamine; ethanol ... See more keywords
The analgesic efficacy and duration of lidocaine on vascular pain induced by hypertonic saline infusion: a double-blinded, randomized control trial
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Anesthesia"
DOI: 10.1007/s00540-019-02628-2
Abstract: PurposeTo determine the analgesic efficacy and analgesic duration of lidocaine 20 mg and 40 mg on eliminating the vascular pain associated with hypertonic saline infusion.MethodPatients who complained pain during infusion of hypertonic saline were randomized into three… read more here.
Keywords: duration; group; lidocaine; hypertonic saline ... See more keywords
Effectiveness of inhaled hypertonic saline application for sputum induction to improve Mycobacterium tuberculosis identification in patients with pulmonary tuberculosis
Sign Up to like & getrecommendations! Published in 2021 at "Wiener Medizinische Wochenschrift"
DOI: 10.1007/s10354-021-00871-5
Abstract: This study assessed the effectiveness and diagnostic significance of hypertonic saline sputum induction for improving Mycobacterium tuberculosis (MTB) detection. A prospective, randomized, open, two-arm, comparative study on MTB identification effectiveness when using inhaled sodium chloride… read more here.
Keywords: hypertonic saline; sputum; group; tuberculosis ... See more keywords
Mannitol and Hypertonic Saline Reduce Swelling and Modulate Inflammatory Markers in a Rat Model of Intracerebral Hemorrhage
Sign Up to like & getrecommendations! Published in 2018 at "Neurocritical Care"
DOI: 10.1007/s12028-018-0535-7
Abstract: BackgroundSpontaneous intracerebral hemorrhage (ICH) leaves most survivors dependent at follow-up. The importance of promoting M2-like microglial responses is increasingly recognized as a key element to ameliorate brain injury following ICH. The osmotherapeutic agents, mannitol and… read more here.
Keywords: intracerebral hemorrhage; mannitol hypertonic; hypertonic saline;
Analyzing the efficacy of frequent sodium checks during hypertonic saline infusion after elective brain tumor surgery
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Neurology and Neurosurgery"
DOI: 10.1016/j.clineuro.2017.02.011
Abstract: OBJECTIVE To assess the utility of frequent sodium checks (every 6h) in patients receiving hypertonic saline (HS) after elective brain tumor surgeries. PATIENTS AND METHODS A single-institution retrospective review of patients having undergone elective craniotomies… read more here.
Keywords: sodium; sodium checks; hypertonic saline; elective brain ... See more keywords
Examining the Effect of Hypertonic Saline Administered for Reduction of Intracranial Hypertension on Coagulation.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the American College of Surgeons"
DOI: 10.1016/j.jamcollsurg.2019.11.011
Abstract: BACKGROUND Hypertonic saline (23.4%, HTS) bolus administration is common practice for refractory intracranial hypertension, but its effects on coagulation are unknown. We hypothesize that 23.4% HTS in whole blood results in progressive impairment of coagulation… read more here.
Keywords: coagulation; blood; intracranial hypertension; hypertonic saline ... See more keywords
Bolus therapy with 3% hypertonic saline or 0.9% saline in emergency department patients with suspected sepsis: A pilot randomised controlled trial.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of critical care"
DOI: 10.1016/j.jcrc.2019.03.009
Abstract: OBJECTIVE AND DESIGN Hypertonic saline administered during fluid resuscitation may mitigate endothelial glycocalyx (EG) shedding and inflammation. The objective of this pilot randomised controlled trial was to measure the effect of hypertonic saline, compared to… read more here.
Keywords: randomised controlled; trial; pilot randomised; group ... See more keywords