Hypertranscription in Development, Stem Cells, and Regeneration.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental cell"
DOI: 10.1016/j.devcel.2016.11.010
Abstract: Cells can globally upregulate their transcriptome during specific transitions, a phenomenon called hypertranscription. Evidence for hypertranscription dates back over 70 years but has gone largely ignored in the genomics era until recently. We discuss data… read more here.
Keywords: hypertranscription development; regeneration; hypertranscription; development stem ... See more keywords
Living Up to the Hype: Protein Synthesis Promotes Hypertranscription in Embryonic Stem Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Cell stem cell"
DOI: 10.1016/j.stem.2018.02.008
Abstract: The rapid proliferation and unlimited self-renewal of embryonic stem cells depends upon a permissive chromatin landscape that enables hypertranscription. In this issue of Cell Stem Cell, Bulut-Karslioglu et al. report that euchromatin and transcriptional output are… read more here.
Keywords: cell; embryonic stem; protein synthesis; stem ... See more keywords