Effect of Trimetazidine Dihydrochloride Therapy on Exercise Capacity in Patients With Nonobstructive Hypertrophic Cardiomyopathy: A Randomized Clinical Trial
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Cardiology"
DOI: 10.1001/jamacardio.2018.4847
Abstract: Importance Hypertrophic cardiomyopathy causes limiting symptoms in patients, mediated partly through inefficient myocardial energy use. There is conflicting evidence for therapy with inhibitors of myocardial fatty acid metabolism in patients with nonobstructive hypertrophic cardiomyopathy. Objective… read more here.
Keywords: therapy; nonobstructive hypertrophic; exercise capacity; hypertrophic cardiomyopathy ... See more keywords
Mortality Among Referral Patients With Hypertrophic Cardiomyopathy vs the General European Population.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2019.4534
Abstract: Importance It is unclear whether hypertrophic cardiomyopathy (HCM) conveys excess mortality when compared with the general population. Objective To compare the survival of patients with HCM with that of the general European population. Design, Setting,… read more here.
Keywords: general european; hypertrophic cardiomyopathy; mortality; patients hcm ... See more keywords
Rare and Common Genetic Variation Underlying the Risk of Hypertrophic Cardiomyopathy in a National Biobank.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA cardiology"
DOI: 10.1001/jamacardio.2022.1061
Abstract: Importance Hypertrophic cardiomyopathy (HCM) is a leading cause of sudden cardiac death in young people. Although rare genetic variants are well-established contributors to HCM risk, common genetic variants have recently been implicated in disease pathogenesis.… read more here.
Keywords: hypertrophic cardiomyopathy; rare common; genetic variants; hcm ... See more keywords
Vigorous Exercise in Patients With Hypertrophic Cardiomyopathy.
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DOI: 10.1001/jamacardio.2023.1042
Abstract: Importance Whether vigorous intensity exercise is associated with an increase in risk of ventricular arrhythmias in individuals with hypertrophic cardiomyopathy (HCM) is unknown. Objective To determine whether engagement in vigorous exercise is associated with increased… read more here.
Keywords: hypertrophic cardiomyopathy; intensity exercise; activity; vigorous exercise ... See more keywords
Energetic drain driving hypertrophic cardiomyopathy
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DOI: 10.1002/1873-3468.13496
Abstract: Hypertrophic cardiomyopathy (HCM) is the most common form of hereditary cardiomyopathy and is mainly caused by mutations of genes encoding cardiac sarcomeric proteins. HCM is characterized by hypertrophy of the left ventricle, frequently involving the… read more here.
Keywords: drain driving; energetic drain; hypertrophic cardiomyopathy; driving hypertrophic ... See more keywords
Long‐term survival after acute myocardial infarction in patients with hypertrophic cardiomyopathy
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DOI: 10.1002/clc.22601
Abstract: Hypertrophic cardiomyopathy (HCM) is associated with poor prognosis. It has been reported that there is no difference in in‐hospital mortality after acute myocardial infarction (AMI) between patients with and without HCM. However, whether there is… read more here.
Keywords: long term; myocardial infarction; hypertrophic cardiomyopathy; acute myocardial ... See more keywords
Clinical and echocardiographic parameters as risk factors for atrial fibrillation in patients with hypertrophic cardiomyopathy
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DOI: 10.1002/clc.23050
Abstract: Atrial fibrillation (AF) is a common complication in patients with hypertrophic cardiomyopathy (HCM) and may contribute to high cardiovascular morbidity and mortality. Therefore, it is important to assess parameters associated with AF in HCM patients. read more here.
Keywords: atrial fibrillation; clinical echocardiographic; echocardiographic parameters; hypertrophic cardiomyopathy ... See more keywords
Prognostic value of global longitudinal strain in hypertrophic cardiomyopathy: A systematic review and meta‐analysis
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DOI: 10.1002/clc.23928
Abstract: As previously reported, impairment of left ventricular global longitudinal strain (LVGLS) is associated with myocardial fibrosis, arrhythmias, and heart failure in hypertrophic cardiomyopathy (HCM) patients. read more here.
Keywords: hypertrophic cardiomyopathy; longitudinal strain; global longitudinal; prognostic value ... See more keywords
Impact of SARS‐Cov‐2 infection in patients with hypertrophic cardiomyopathy: results of an international multicentre registry
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DOI: 10.1002/ehf2.13964
Abstract: To describe the natural history of SARS‐CoV‐2 infection in patients with hypertrophic cardiomyopathy (HCM) compared with a control group and to identify predictors of adverse events. read more here.
Keywords: hypertrophic cardiomyopathy; patients hypertrophic; infection patients; cov infection ... See more keywords
Very long‐term prognosis in patients with hypertrophic cardiomyopathy: a longitudinal study with a period of 20 years
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DOI: 10.1002/ehf2.13983
Abstract: We aim to clarify the prognosis on patients with hypertrophic cardiomyopathy (HCM) for a follow‐up period of more than 10 years. read more here.
Keywords: period years; hypertrophic cardiomyopathy; patients hypertrophic; prognosis patients ... See more keywords
Blood‐based biomarkers for the prediction of hypertrophic cardiomyopathy prognosis: a systematic review and meta‐analysis
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DOI: 10.1002/ehf2.14073
Abstract: Hypertrophic cardiomyopathy (HCM) is the most prevalent monogenic heart disease. HCM is an important cause of sudden cardiac death and may also lead to outflow tract obstruction and heart failure. Disease severity is highly variable… read more here.
Keywords: hypertrophic cardiomyopathy; review; biomarkers prediction; based biomarkers ... See more keywords