TGF-β Signalling is Suppressed under Pro-Hypertrophic Conditions in MSC Chondrogenesis Due to TGF-β Receptor Downregulation
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DOI: 10.15283/ijsc18088
Abstract: Background and Objectives Mesenchymal stem cells (MSCs) become hypertrophic in long term despite chondrogenic differentiation following the pathway of growth plate chondrocytes. This terminal differentiation leads to phenotypically unstable cartilage and was mirrored in vitro… read more here.
Keywords: pro hypertrophic; hypertrophic conditions; tgf; hypertrophy ... See more keywords