Articles with "hyperuricemic patients" as a keyword



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Open-label study of long-term administration of dotinurad in Japanese hyperuricemic patients with or without gout

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Published in 2019 at "Clinical and Experimental Nephrology"

DOI: 10.1007/s10157-019-01831-5

Abstract: Background Dotinurad is a novel selective urate reabsorption inhibitor (SURI) which reduces serum uric acid levels by selectively inhibiting urate transporter 1 (URAT1). This study was intended to verify the efficacy and safety of dotinurad… read more here.

Keywords: uric acid; long term; hyperuricemic patients; serum uric ... See more keywords
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Comparative efficacy and safety of topiroxostat at different dosages in hyperuricemic patients with or without gout: A network meta-analysis of randomized controlled trials.

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Published in 2021 at "International journal of clinical pharmacology and therapeutics"

DOI: 10.5414/cp204108

Abstract: OBJECTIVE We aimed to assess the relative efficacy and safety of topiroxostat at different dosages in hyperuricemic patients with or without gout. MATERIALS AND METHODS A Bayesian network meta-analysis was performed to combine direct and… read more here.

Keywords: efficacy safety; patients without; hyperuricemic patients; topiroxostat ... See more keywords