Dual function of Rab1A in secretion and autophagy: hypervariable domain dependence
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DOI: 10.26508/lsa.202201810
Abstract: Gyurkovska et al show that whereas both Rab1A and Rab1B regulate secretion, Rab1A-HVD enables it to localize to autophagosomes and regulate autophagy. This provides a mechanism for a dual functionality of a single Rab in… read more here.
Keywords: secretion autophagy; rab1a; hypervariable domain; secretion ... See more keywords
Identification of a non-canonical G3BP-binding sequence in a Mayaro virus nsP3 hypervariable domain
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.958176
Abstract: Ras-GTPase-activating SH3 domain-binding-proteins 1 (G3BP1) and 2 (G3BP2) are multifunctional RNA-binding proteins involved in stress granule nucleation, previously identified as essential cofactors of Old World alphaviruses. They are recruited to viral replication complexes formed by… read more here.
Keywords: hypervariable domain; virus; sequence; g3bp binding ... See more keywords