Short Communication: Manα1-2Man-Binding Anti-HIV Lectins Enhance the Exposure of V2i and V3 Crown Neutralization Epitopes on the V1/V2 and V3 Hypervariable Loops of HIV-1 Envelope
Sign Up to like & getrecommendations! Published in 2017 at "AIDS Research and Human Retroviruses"
DOI: 10.1089/aid.2016.0262
Abstract: Abstract This study aimed to explore the contribution of high-mannose glycans in the masking of conserved V3 crown (GPG) and V2i epitopes on the hypervariable loops of most exposed distal surface of HIV-1 Env. Using… read more here.
Keywords: hypervariable loops; 2man binding; hiv; epitopes hypervariable ... See more keywords
The Hypervariable Loops of Free TCRs Sample Multiple Distinct Metastable Conformations in Solution
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2018.00095
Abstract: CD4+ and CD8+ αβ T cell antigen recognition is determined by the interaction between the TCR Complementarity Determining Region (CDR) loops and the peptide-presenting MHC complex. These T cells are known for their ability to… read more here.
Keywords: hypervariable loops; free tcrs; solution; tcrs sample ... See more keywords