HYPK promotes the activity of the Nα-acetyltransferase A complex to determine proteostasis of nonAc-X2/N-degron–containing proteins
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DOI: 10.1126/sciadv.abn6153
Abstract: In humans, the Huntingtin yeast partner K (HYPK) binds to the ribosome-associated Nα-acetyltransferase A (NatA) complex that acetylates ~40% of the proteome in humans and Arabidopsis thaliana. However, the relevance of HsHYPK for determining the… read more here.
Keywords: acetyltransferase; nonac degron; degron; activity ... See more keywords