Hypoxic mesenchymal stem cell-derived exosomes promote bone fracture healing by the transfer of miR-126.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.12.020
Abstract: Increasing evidence has suggested that paracrine mechanisms might be involved in the underlying mechanism of mesenchymal stem cells (MSCs) transplantation, and exosomes are an important component of this paracrine role. However, MSCs are usually exposed… read more here.
Keywords: hypo exos; bone fracture; mir 126; fracture ... See more keywords
Exosomes Derived From Hypoxia-Conditioned Stem Cells of Human Deciduous Exfoliated Teeth Enhance Angiogenesis via the Transfer of let-7f-5p and miR-210-3p
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.879877
Abstract: Physiological root resorption of deciduous teeth is a normal phenomenon. How the angiogenesis process is regulated to provide adequate levels of oxygen and nutrients in hypoxic conditions when the dental pulp tissue is reduced at… read more here.
Keywords: mir 210; let mir; hypo exos; angiogenesis via ... See more keywords
Hypoxia Alters the Proteome Profile and Enhances the Angiogenic Potential of Dental Pulp Stem Cell-Derived Exosomes
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DOI: 10.3390/biom12040575
Abstract: Dental pulp stem cells (DPSCs) and their exosomes (Exos) are effective treatments for regenerative medicine. Hypoxia was confirmed to improve the angiogenic potential of stem cells. However, the angiogenic effect and mechanism of hypoxia-preconditioned DPSC-Exos… read more here.
Keywords: proteome profile; exos; hypo exos; angiogenic potential ... See more keywords
Exosomes Derived from Glioma Cells under Hypoxia Promote Angiogenesis through Up-regulated Exosomal Connexin 43
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Medical Sciences"
DOI: 10.7150/ijms.71912
Abstract: Glioblastoma multiform (GBM) is a highly aggressive primary brain tumor. Exosomes derived from glioma cells under a hypoxic microenvironment play an important role in tumor biology including metastasis, angiogenesis and chemoresistance. However, the underlying mechanisms… read more here.
Keywords: proliferation; cx43; hypo exos; exosomes derived ... See more keywords