Distinct pathways drive anterior hypoblast specification in the implanting human embryo
Sign Up to like & getrecommendations! Published in 2024 at "Nature Cell Biology"
DOI: 10.1038/s41556-024-01367-1
Abstract: Development requires coordinated interactions between the epiblast, which generates the embryo proper; the trophectoderm, which generates the placenta; and the hypoblast, which forms both the anterior signalling centre and the yolk sac. These interactions remain… read more here.
Keywords: hypoblast; hypoblast specification; specification; anterior hypoblast ... See more keywords
MEK signalling pathway is required for hypoblast specification and migration in ovine.
Sign Up to like & getrecommendations! Published in 2024 at "Reproduction"
DOI: 10.1530/rep-24-0003
Abstract: Early embryo development requires the differentiation of three cell lineages in two differentiation events. The second lineage specification differentiates the inner cell mass into epiblast, which will form the proper foetus, and hypoblast, which together… read more here.
Keywords: hypoblast specification; pathway required; specification; signalling pathway ... See more keywords