MYOSIN LIGHT CHAIN DEPHOSPHORYLATION BY PPP1R12C PROMOTES ATRIAL HYPOCONTRACTILITY IN ATRIAL FIBRILLATION
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DOI: 10.1016/s0735-1097(20)31000-7
Abstract: Atrial fibrillation (AF) increases stroke risk five-fold. Atrial hypocontractility from atrial myosin light chain (MLC2a) dephosphorylation contributes to stroke risk in AF. Recent proteomic data has shown increased protein phosphatase 1 subunit 12C (PPP1R12C) targeting… read more here.
Keywords: atrial fibrillation; atrial hypocontractility; myosin light; hypocontractility atrial ... See more keywords